4,4'-Bis(methoxymethyl)-1,1'-biphenyl

Base Information

• Chemical Name: 4,4'-Bis(methoxymethyl)-1,1'-biphenyl
• CAS No.: 3753-18-2
• Molecular Formula: C16H18O2
• Molecular Weight: 242.318
• Hs Code.: 2909309090
• European Community (EC) Number: 700-008-0
• DSSTox Substance ID: DTXSID60364039
• Nikkaji Number: J1.226.630H
• Wikidata: Q72446198
• Mol file: 3753-18-2.mol

Synonyms:4,4'-Bis(methoxymethyl)-1,1'-biphenyl;3753-18-2;4,4'-Bis(methoxymethyl)biphenyl;1-(methoxymethyl)-4-[4-(methoxymethyl)phenyl]benzene;4,4-Bis-(methoxy-mehtyl) biphenyl;1,1'-Biphenyl, 4,4'-bis(methoxymethyl)-;4,4-bis(methoxymethyl)biphenyl;EC 700-008-0;bismethoxymethylbiphenyl;SCHEMBL198803;DTXSID60364039;MFCD03840532;AKOS015911197;AB16457;AC-12936;AS-12595;4,4'-Dis(Methoxy-methyl)-1,1'-Biphenyl;4,4\'-Bis(methoxymethyl)-1,1\'-biphenyl;B3046;FT-0635005;D88978;A823731

Chemical Property of 4,4'-Bis(methoxymethyl)-1,1'-biphenyl

Chemical Property:

• Vapor Pressure: 0Pa at 25℃
• Melting Point: 49-50 °C
• Boiling Point: 337.3 °C at 760 mmHg
• Flash Point: 125.4 °C
• PSA: 18.46000
• Density: 1.039 g/cm³
• LogP: 3.64640
• Solubility.: soluble in Toluene
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 242.130679813
• Heavy Atom Count: 18
• Complexity: 189

Purity/Quality:

99.9% ^*data from raw suppliers

4,4''-Bis(methoxymethyl)-1,1''-biphenyl ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCC1=CC=C(C=C1)C2=CC=C(C=C2)COC

Technology Process of 4,4'-Bis(methoxymethyl)-1,1'-biphenyl

There total 5 articles about 4,4'-Bis(methoxymethyl)-1,1'-biphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-chlorobenzyl methyl ether (1195-44-4) → 4,4′-bis(methoxymethyl)biphenyl (3753-18-2)

Guidance literature:

With zinc; 5-trimethylsilyl-2,2'-bipyridine; nickel dibromide; In 1-methyl-pyrrolidin-2-one; at 20 - 70 ℃; Inert atmosphere;

Reference yield:

biphenyl (92-52-4,1594-86-1) + Dimethoxymethane (109-87-5) → 4-(methoxymethyl)-1,1'-biphenyl (86130-05-4) + 4,4′-bis(methoxymethyl)biphenyl (3753-18-2)

Guidance literature:

mordenite SiO₂/Al₂O₃ 90; In cyclohexane; at 120 ℃; for 4h; Product distribution / selectivity;

Reference yield:

diethyl 2-(cycloheptene-1-yl)-cyclobuten-1-yl phosphate + 4-(methoxymethyl)phenylzinc chloride lithium chloride → 4,4′-bis(methoxymethyl)biphenyl (3753-18-2) + 1-cycloheptenyl-2-[4-(methoxymethyl)phenyl]cyclobutene

Guidance literature:

With aluminum (III) chloride; C₃₆H₂₈Cl₂OP₂Pd; In tetrahydrofuran; at 50 ℃; for 17h; Overall yield = 73 %; Overall yield = 0.451 g;

DOI:10.1002/ejoc.201801522

upstream raw materials:

biphenyl

Dimethoxymethane

4-chlorobenzyl methyl ether

Refernces

• 1、 -. "Polymer having antireflective properties, hardmask composition including the same, process for forming a patterned material layer, and associated device". . . Retrieved 2010/02/17.
• 2、 -. "TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND WITH THE TRANSITION METAL COMPLEX". Page/Page column 44. . Retrieved 2010/06/17.