(4S,5R)-1,3-Dibenzyl-2-oxo-imidazolidine-4,5-dicarboxylic acid dipropyl ester

Base Information

• Chemical Name: (4S,5R)-1,3-Dibenzyl-2-oxo-imidazolidine-4,5-dicarboxylic acid dipropyl ester
• CAS No.: 83889-74-1
• Molecular Formula: C₂₅H₃₀N₂O₅
• Molecular Weight: 438.524
• Mol file: 83889-74-1.mol

Synonyms:(4S,5R)-1,3-Dibenzyl-2-oxo-imidazolidine-4,5-dicarboxylic acid dipropyl ester

Chemical Property of (4S,5R)-1,3-Dibenzyl-2-oxo-imidazolidine-4,5-dicarboxylic acid dipropyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4S,5R)-1,3-Dibenzyl-2-oxo-imidazolidine-4,5-dicarboxylic acid dipropyl ester

There total 1 articles about (4S,5R)-1,3-Dibenzyl-2-oxo-imidazolidine-4,5-dicarboxylic acid dipropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

propan-1-ol (71-23-8) + cis-1,3-dibenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid (51591-75-4,634188-82-2) → (4S,5R)-1,3-Dibenzyl-2-oxo-imidazolidine-4,5-dicarboxylic acid dipropyl ester (83889-74-1)

Guidance literature:

With thionyl chloride; for 1.5h; Heating;

Reference yield: 85.0%

(4S,5R)-1,3-Dibenzyl-2-oxo-imidazolidine-4,5-dicarboxylic acid dipropyl ester (83889-74-1) → (4S,5R)-1,3-dibenzyl-5-(n-propoxycarbonyl)-2-oxo-imidazolidine-4-carboxylic acid (83889-76-3)

Guidance literature:

With phosphate buffer; In acetone; at 25 ℃; for 24h; pig liver esterase;

Reference yield:

(4S,5R)-1,3-Dibenzyl-2-oxo-imidazolidine-4,5-dicarboxylic acid dipropyl ester (83889-74-1) → (3aS,6aR)-1,3-dibenzyltetrahydro-1H-furo[3,4-d]imidazole-2,4-dione (28092-62-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / phosphate buffer / acetone / 24 h / 25 °C / pig liver esterase

2: LiBH₄

With lithium borohydride; phosphate buffer; In acetone;

upstream raw materials:

propan-1-ol

cis-1,3-dibenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid

Downstream raw materials:

(4S,5R)-1,3-dibenzyl-5-(n-propoxycarbonyl)-2-oxo-imidazolidine-4-carboxylic acid

(3aS,6aR)-1,3-dibenzyltetrahydro-1H-furo[3,4-d]imidazole-2,4-dione

(4S,5R)-1,3-dibenzyl-5-hydroxymethyl-2-oxoimidazolidine-4-carboxylic acid lactone