8-formyl-5,6,7-trihydroxyflavone

Base Information

• Chemical Name: 8-formyl-5,6,7-trihydroxyflavone
• CAS No.: 791838-62-5
• Molecular Formula: C₁₆H₁₀O₆
• Molecular Weight: 298.252
• Mol file: 791838-62-5.mol

Synonyms:8-formyl-5,6,7-trihydroxyflavone

Chemical Property of 8-formyl-5,6,7-trihydroxyflavone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 8-formyl-5,6,7-trihydroxyflavone

There total 2 articles about 8-formyl-5,6,7-trihydroxyflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

8-formyl-5-hydroxy-6,7-dimethoxyflavone → 8-formyl-5,6,7-trihydroxyflavone (791838-62-5)

Guidance literature:

With boron tribromide; In dichloromethane; at -80 - 20 ℃;

DOI:10.1271/bbb.68.369

Reference yield:

mosloflavone (740-33-0) → 8-formyl-5,6,7-trihydroxyflavone (791838-62-5)

Guidance literature:

Multi-step reaction with 2 steps

1: trifluoroacetic acid / 24 h / Heating

2: 75 percent / boron tribromide / CH₂Cl₂ / -80 - 20 °C

With boron tribromide; trifluoroacetic acid; In dichloromethane; 1: Duff reaction;

DOI:10.1271/bbb.68.369

Reference yield: 65.0%

8-formyl-5,6,7-trihydroxyflavone (791838-62-5) → 5,6,7-trihydroxy-8-methylflavone (374705-41-6)

Guidance literature:

With methyl orange; sodium cyanoborohydride; In tetrahydrofuran; at 20 ℃; for 3h;

DOI:10.1271/bbb.68.369

upstream raw materials:

mosloflavone

Downstream raw materials:

5,6,7-trihydroxy-8-methylflavone