5-Methylsalicylic acid

Base Information

Chemical Name:5-Methylsalicylic acid
CAS No.:89-56-5
Molecular Formula:C8H8O3
Molecular Weight:152.15
Hs Code.:29182110
European Community (EC) Number:201-918-6
NSC Number:38518
UNII:6GAI2MTV5V
DSSTox Substance ID:DTXSID20237472
Nikkaji Number:J4.305B
Wikipedia:5-Methylsalicylic_acid
Wikidata:Q27264861
ChEMBL ID:CHEMBL1161012
Mol file:89-56-5.mol

Synonyms:5-methyl salicylic acid;5-methylsalicylic acid;5mS acid

Suppliers and Price of 5-Methylsalicylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AHH
5-Methylsalicylic acid 98%
100g
$ 345.00

AK Scientific
2-Hydroxy-5-methylbenzoicacid
500g
$ 240.00

AK Scientific
2-Hydroxy-5-methylbenzoicacid
25g
$ 47.00

Alfa Aesar
5-Methylsalicylic acid, 98%
5g
$ 52.40

Alfa Aesar
5-Methylsalicylic acid, 98%
25g
$ 212.00

Alichem
2-Hydroxy-5-methylbenzoicacid
250mg
$ 489.60

Alichem
2-Hydroxy-5-methylbenzoicacid
500mg
$ 863.90

Alichem
2-Hydroxy-5-methylbenzoicacid
1g
$ 1460.20

Ambeed
5-Methylsalicylic acid 98%
500g
$ 307.00

Ambeed
5-Methylsalicylic acid 98%
100g
$ 87.00

Total 64 raw suppliers

Chemical Property of 5-Methylsalicylic acid

Chemical Property:

Appearance/Colour:odorless white crystals
Vapor Pressure:0.00052mmHg at 25°C
Melting Point:163-165 °C(lit.)
Refractive Index:1.4945 (estimate)
Boiling Point:299.8 °C at 760 mmHg
PKA:pK1:4.08 (25°C)
Flash Point:149.3 °C
PSA：57.53000
Density:1.304 g/cm³
LogP:1.39880
Storage Temp.:Sealed in dry,Room Temperature
Water Solubility.:21.9g/L(100 oC)
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:152.047344113
Heavy Atom Count:11
Complexity:155

Purity/Quality:

99%, ^*data from raw suppliers

5-Methylsalicylic acid 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,Xi
Hazard Codes:Xn,Xi
Statements: 22-37/38-41-36/37/38
Safety Statements: 26-36/39-22-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)O)C(=O)O
Uses Toxicity is similar to salicylic acid. 5-Methylsalicylic acid is used in manufacturing of dyes. 5-Methylsalicylic acid was used in generation of o-sulfate conjugates in situ and their analysis by ultra-performance liquid chromatography-time-of-flight mass spectrometry.

Technology Process of 5-Methylsalicylic acid

There total 95 articles about 5-Methylsalicylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 106-44-5
p-cresol

: 17201-44-4
sodium ethyl carbonate

: 89-56-5
5-Methylsalicylic acid

Guidance literature:: With carbon dioxide; at 185 ℃; for 7h; under 7600.51 Torr; Temperature; Pressure; Concentration; regioselective reaction; Autoclave;
DOI:10.1134/S0965544116070161

Reference yield: 87.0%

: 6342-60-5
2-chloro-5-methyl-benzoic acid

: 89-56-5
5-Methylsalicylic acid

Guidance literature:: With pyridine; copper; potassium carbonate; In water; for 2h; Heating;
DOI:10.1081/SCC-120004857

Reference yield: 85.0%

: 99-04-7
m-Toluic acid

: 89-56-5
5-Methylsalicylic acid

Guidance literature:: With tert.-butylhydroperoxide; (2S,3S)-N-acetyl-2-amino-3-methylpentanoic acid; potassium acetate; palladium diacetate; p-benzoquinone; In 1,2-dimethoxyethane; water; at 100 ℃;
DOI:10.1016/j.tetlet.2021.153434