2,6-Difluorobenzamide

Base Information

Chemical Name:2,6-Difluorobenzamide
CAS No.:18063-03-1
Molecular Formula:C7H5F2NO
Molecular Weight:157.12
Hs Code.:2924.29
European Community (EC) Number:241-972-8
UNII:SJ2RN214MK
DSSTox Substance ID:DTXSID4073417
Nikkaji Number:J43.076E
Wikidata:Q15632832
Mol file:18063-03-1.mol

Synonyms:2,6-difluorobenzamide

Suppliers and Price of 2,6-Difluorobenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,6-Difluorobenzamide
10g
$ 70.00

TRC
2,6-Difluorobenzamide
1g
$ 45.00

TCI Chemical
2,6-Difluorobenzamide >97.0%(N)
25g
$ 20.00

SynQuest Laboratories
2,6-Difluorobenzamide 98%
25 g
$ 10.00

SynQuest Laboratories
2,6-Difluorobenzamide 98%
100 g
$ 35.00

SynQuest Laboratories
2,6-Difluorobenzamide 98%
500 g
$ 95.00

Sigma-Aldrich
2,6-Difluorobenzamide 97%
50g
$ 85.40

Sigma-Aldrich
2,6-Difluorobenzamide 97%
10g
$ 31.10

Matrix Scientific
2,6-Difluorobenzamide 97%
100g
$ 52.00

Matrix Scientific
2,6-Difluorobenzamide 97%
25g
$ 16.00

Total 171 raw suppliers

Chemical Property of 2,6-Difluorobenzamide

Chemical Property:

Appearance/Colour:white powder
Vapor Pressure:0.622mmHg at 25°C
Melting Point:145-148 °C(lit.)
Refractive Index:1,508
Boiling Point:187.7 °C at 760 mmHg
PKA:14.54±0.50(Predicted)
Flash Point:67.3 °C
PSA：43.09000
Density:1.348 g/cm³
LogP:1.76400
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:ethanol: soluble5%, clear to turbid, colorless to light yellow
XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:157.03392011
Heavy Atom Count:11
Complexity:153

Purity/Quality:

99% ^*data from raw suppliers

2,6-Difluorobenzamide ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi,Xn
Hazard Codes:Xi,Xn
Statements: 36/37/38-20
Safety Statements: 26-37/39-36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C(=C1)F)C(=O)N)F
Description 2,6-Difluorobenzamide is a major metabolite of pesticide diflubenzuron and has been quantitated by HPLC/diode-array method.
Uses 2,6-Difluorobenzamide (CAS# 18063-03-1) is a useful building block used in the synthesis of (E)-3-methyleneisoindolin-1-ones via oxidative annulation acrylates.

Technology Process of 2,6-Difluorobenzamide

There total 15 articles about 2,6-Difluorobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1897-52-5
2,6 difluorobenzonitrile

: 18063-03-1
2,6-difluorobenzamide

Guidance literature:: With water; nitrile hydratase from Rhodococcus rhodochrous J₁; at 25 ℃; for 22h; KH₂PO₄-K₂HPO₄ puffer pH=8.0;
DOI:10.1016/0040-4020(89)80133-4

Reference yield: 92.0%

: 19064-16-5
2,6-difluoro-benzaldehyde oxime

: 18063-03-1
2,6-difluorobenzamide

Guidance literature:: With sulfuric acid; at 125 ℃; for 0.75h;

Reference yield: 81.0%

: 437-81-0
2,6-difluorobenzaldehyde

: 18063-03-1
2,6-difluorobenzamide

Guidance literature:: With tert.-butylhydroperoxide; titanium superoxide; saccharin; In 1,4-dioxane; hexane; at 90 ℃; for 1h; Green chemistry;
DOI:10.1039/c9ra10413e