C₂₅H₁₆F₆N₈O₃

Base Information

• Chemical Name: C₂₅H₁₆F₆N₈O₃
• CAS No.: 1427002-76-3
• Molecular Formula: C₂₅H₁₆F₆N₈O₃
• Molecular Weight: 590.444
• Mol file: 1427002-76-3.mol

Synonyms:C₂₅H₁₆F₆N₈O₃

Chemical Property of C₂₅H₁₆F₆N₈O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₁₆F₆N₈O₃

There total 3 articles about C₂₅H₁₆F₆N₈O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C23H17F3N8O2 (1427002-67-2) + trifluoroacetic anhydride (407-25-0) → C25H16F6N8O3 (1427002-76-3)

Guidance literature:

With 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; at 60 - 70 ℃; for 1h; Inert atmosphere; Green chemistry;

DOI:10.2298/JSC120409082S

Reference yield:

1-Phenyl-4,4,4-trifluorobutane-1,3-dione (326-06-7) → C25H16F6N8O3 (1427002-76-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: hydrogenchloride; sodium nitrite / water / 0 - 2 °C

1.2: 1 h / 0 - 2 °C

2.1: ammonia / water / 0.5 h / pH 7 / Reflux; Green chemistry

3.1: 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate / 1 h / 60 - 70 °C / Inert atmosphere; Green chemistry

With hydrogenchloride; ammonia; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; sodium nitrite; In water;

DOI:10.2298/JSC120409082S

Reference yield:

1H-benzimidazol-2-amine (934-32-7) → C25H16F6N8O3 (1427002-76-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: hydrogenchloride; sodium nitrite / water / 0 - 2 °C

1.2: 1 h / 0 - 2 °C

2.1: ammonia / water / 0.5 h / pH 7 / Reflux; Green chemistry

3.1: 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate / 1 h / 60 - 70 °C / Inert atmosphere; Green chemistry

With hydrogenchloride; ammonia; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; sodium nitrite; In water;

DOI:10.2298/JSC120409082S

upstream raw materials:

C₂₃H₁₇F₃N₈O₂

trifluoroacetic anhydride

1H-benzimidazol-2-amine

1-Phenyl-4,4,4-trifluorobutane-1,3-dione