(2S)-2-(1-(6-fluoro-3'-methylbiphenyl-2-yl)-5-methoxypentyl)morpholine hydrochloride

Base Information

Chemical Name:(2S)-2-(1-(6-fluoro-3'-methylbiphenyl-2-yl)-5-methoxypentyl)morpholine hydrochloride
CAS No.:952593-53-2
Molecular Formula:C₂₃H₃₀FNO₂*ClH
Molecular Weight:407.956
Hs Code.:

Synonyms:(2S)-2-(1-(6-fluoro-3'-methylbiphenyl-2-yl)-5-methoxypentyl)morpholine hydrochloride

Suppliers and Price of (2S)-2-(1-(6-fluoro-3'-methylbiphenyl-2-yl)-5-methoxypentyl)morpholine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S)-2-(1-(6-fluoro-3'-methylbiphenyl-2-yl)-5-methoxypentyl)morpholine hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S)-2-(1-(6-fluoro-3'-methylbiphenyl-2-yl)-5-methoxypentyl)morpholine hydrochloride

There total 7 articles about (2S)-2-(1-(6-fluoro-3'-methylbiphenyl-2-yl)-5-methoxypentyl)morpholine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: (2S)-tert-butyl 2-(1-(6-fluoro-3'-methylbiphenyl-2-yl)-5-methoxypentyl)morpholine-4-carboxylate

: 952593-53-2
(2S)-2-(1-(6-fluoro-3'-methylbiphenyl-2-yl)-5-methoxypentyl)morpholine hydrochloride

Guidance literature:: With hydrogenchloride; In methanol; at 50 ℃; for 0.166667h;

Reference yield:

: 952593-49-6
(R)-tert-butyl 2-((R)-1-(6-fluoro-3'-methylbiphenyl-2-yl)-1-hydroxy-5-methoxypentyl)-morpholine-4-carboxylate

: 952593-53-2
(2S)-2-(1-(6-fluoro-3'-methylbiphenyl-2-yl)-5-methoxypentyl)morpholine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: Burgess Reagent / toluene / 2 h / Heating / reflux

2: hydrogen / palladium dihydroxide / methanol / 48 h

3: hydrogenchloride / methanol / 0.17 h / 50 °C

With hydrogenchloride; Burgess Reagent; hydrogen; palladium dihydroxide; In methanol; toluene;

Reference yield:

: 884512-78-1
6-bromo-2-fluoro-3'-methyl-biphenyl

: 952593-53-2
(2S)-2-(1-(6-fluoro-3'-methylbiphenyl-2-yl)-5-methoxypentyl)morpholine hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1: n-butyllithium / diethyl ether; pentane / -78 - -70 °C

2: diethyl ether; toluene; pentane / -20 - 20 °C

3: Burgess Reagent / toluene / 2 h / Heating / reflux

4: hydrogen / palladium dihydroxide / methanol / 48 h

5: hydrogenchloride / methanol / 0.17 h / 50 °C

With hydrogenchloride; n-butyllithium; Burgess Reagent; hydrogen; palladium dihydroxide; In methanol; diethyl ether; toluene; pentane;