(R)-3-(1H-indol-3-yl)-1-[N-(2-methoxybenzyl)amino]-2-(N-triphenylmethylamino)propane

Base Information

Chemical Name:(R)-3-(1H-indol-3-yl)-1-[N-(2-methoxybenzyl)amino]-2-(N-triphenylmethylamino)propane
CAS No.:175460-96-5
Molecular Formula:C₃₈H₃₇N₃O
Molecular Weight:551.731
Hs Code.:

Synonyms:(R)-3-(1H-indol-3-yl)-1-[N-(2-methoxybenzyl)amino]-2-(N-triphenylmethylamino)propane

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-3-(1H-indol-3-yl)-1-[N-(2-methoxybenzyl)amino]-2-(N-triphenylmethylamino)propane

Chemical Property:

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Technology Process of (R)-3-(1H-indol-3-yl)-1-[N-(2-methoxybenzyl)amino]-2-(N-triphenylmethylamino)propane

There total 8 articles about (R)-3-(1H-indol-3-yl)-1-[N-(2-methoxybenzyl)amino]-2-(N-triphenylmethylamino)propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 170508-01-7
(R)-3-(1H-indol-3-yl)-N-(2-methoxybenzyl)-2-(N-triphenylmethylamino)-propanamide

: 175460-96-5
(R)-3-(1H-indol-3-yl)-1-[N-(2-methoxybenzyl)amino]-2-(N-triphenylmethylamino)propane

: 174225-59-3
3-(1H-indol-3-yl)-1-[N-(2-methoxybenzyl) acetylamino]-2-(N-triphenylmethylamino)propane

Guidance literature:: With sodium bis(2-methoxyethoxy)aluminum dihydride; acetic anhydride; triethylamine; In water; toluene;

Reference yield:

: 170508-01-7
(R)-3-(1H-indol-3-yl)-N-(2-methoxybenzyl)-2-(N-triphenylmethylamino)-propanamide

: 175460-96-5
(R)-3-(1H-indol-3-yl)-1-[N-(2-methoxybenzyl)amino]-2-(N-triphenylmethylamino)propane

Guidance literature:: With sodium bis(2-methoxyethoxy)aluminium dihydride; In toluene; Heating;
DOI:10.1021/jo00126a069

Reference yield:

: 6850-57-3
2-methoxybenzylamine

: 175460-96-5
(R)-3-(1H-indol-3-yl)-1-[N-(2-methoxybenzyl)amino]-2-(N-triphenylmethylamino)propane

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) N-methylmorpholine, 2-chloro-4,6-dimethoxy-1,3,5-triazine / 1.) THF, 25 deg C, 1 h

2: Red-Al / toluene / Heating

With 4-methyl-morpholine; 2-chloro-4,6-dimethoxy-1 ,3,5-triazine; sodium bis(2-methoxyethoxy)aluminium dihydride; In toluene;
DOI:10.1021/jo00126a069