Technology Process of C21H24N2O2
There total 6 articles about C21H24N2O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; cesium fluoride;
In
N,N-dimethyl-formamide;
at 60 ℃;
for 3h;
Inert atmosphere;
DOI:10.1021/jm2005404
- Guidance literature:
-
Multi-step reaction with 5 steps
1: pyridine / dichloromethane / 1 h / 20 °C
2: bromine; acetic acid / 1 h / 20 °C
3: methanol; potassium carbonate / 20 °C
4: N,N-diethylaniline / 220 °C
5: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; cesium fluoride / N,N-dimethyl-formamide / 3 h / 60 °C / Inert atmosphere
With
pyridine; methanol; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; bromine; potassium carbonate; acetic acid; cesium fluoride; N,N-diethylaniline;
In
dichloromethane; N,N-dimethyl-formamide;
4: Wittig reaction / 5: Suzuki-Miyaura cross-coupling reaction;
DOI:10.1021/jm2005404
- Guidance literature:
-
Multi-step reaction with 4 steps
1: bromine; acetic acid / 1 h / 20 °C
2: methanol; potassium carbonate / 20 °C
3: N,N-diethylaniline / 220 °C
4: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; cesium fluoride / N,N-dimethyl-formamide / 3 h / 60 °C / Inert atmosphere
With
methanol; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; bromine; potassium carbonate; acetic acid; cesium fluoride; N,N-diethylaniline;
In
N,N-dimethyl-formamide;
3: Wittig reaction / 4: Suzuki-Miyaura cross-coupling reaction;
DOI:10.1021/jm2005404
