methyl 3-(5-{4-[(4-{[(2E,2Z)-2-(4-cyanophenyl)-2-(methoxyimino)ethyl]oxy}benzyl)amino]phenyl}-3-methyl-1,2-oxazol-4-yl)propanoate

Base Information

Chemical Name:methyl 3-(5-{4-[(4-{[(2E,2Z)-2-(4-cyanophenyl)-2-(methoxyimino)ethyl]oxy}benzyl)amino]phenyl}-3-methyl-1,2-oxazol-4-yl)propanoate
CAS No.:1356600-57-1
Molecular Formula:C₃₁H₃₀N₄O₅
Molecular Weight:538.603
Hs Code.:

Synonyms:methyl 3-(5-{4-[(4-{[(2E,2Z)-2-(4-cyanophenyl)-2-(methoxyimino)ethyl]oxy}benzyl)amino]phenyl}-3-methyl-1,2-oxazol-4-yl)propanoate

Suppliers and Price of methyl 3-(5-{4-[(4-{[(2E,2Z)-2-(4-cyanophenyl)-2-(methoxyimino)ethyl]oxy}benzyl)amino]phenyl}-3-methyl-1,2-oxazol-4-yl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 3-(5-{4-[(4-{[(2E,2Z)-2-(4-cyanophenyl)-2-(methoxyimino)ethyl]oxy}benzyl)amino]phenyl}-3-methyl-1,2-oxazol-4-yl)propanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 3-(5-{4-[(4-{[(2E,2Z)-2-(4-cyanophenyl)-2-(methoxyimino)ethyl]oxy}benzyl)amino]phenyl}-3-methyl-1,2-oxazol-4-yl)propanoate

There total 9 articles about methyl 3-(5-{4-[(4-{[(2E,2Z)-2-(4-cyanophenyl)-2-(methoxyimino)ethyl]oxy}benzyl)amino]phenyl}-3-methyl-1,2-oxazol-4-yl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.9%

: 1356600-55-9
4-[(1E,1Z)-2-(4-formylphenoxy)-N-methoxyethanimidoyl]benzonitrile

: 1356600-54-8
methyl 3-[5-(4-aminophenyl)-3-methyl-1,2-oxazol-4-yl]propanoate

: 1356600-57-1
methyl 3-(5-{4-[(4-{[(2E,2Z)-2-(4-cyanophenyl)-2-(methoxyimino)ethyl]oxy}benzyl)amino]phenyl}-3-methyl-1,2-oxazol-4-yl)propanoate

Guidance literature:: 4-[(1E,1Z)-2-(4-formylphenoxy)-N-methoxyethanimidoyl]benzonitrile; methyl 3-[5-(4-aminophenyl)-3-methyl-1,2-oxazol-4-yl]propanoate; With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 0 - 20 ℃; for 16h;

With water; In 1,2-dichloro-ethane; at 20 ℃;

Reference yield:

: 555-16-8
4-nitrobenzaldehdye

: 1356600-57-1
methyl 3-(5-{4-[(4-{[(2E,2Z)-2-(4-cyanophenyl)-2-(methoxyimino)ethyl]oxy}benzyl)amino]phenyl}-3-methyl-1,2-oxazol-4-yl)propanoate

Guidance literature:: Multi-step reaction with 7 steps

1.1: sodium hydroxide / water / 0 - 20 °C

2.1: hydroxylamine hydrochloride; pyridine / ethanol / 4 h / 70 °C / Inert atmosphere

3.1: potassium iodide; sodium hydrogencarbonate; iodine / water; tetrahydrofuran / 100 °C / Inert atmosphere

4.1: sulfuric acid; N-iodo-succinimide / 1,2-dichloro-ethane / 4 h / 0 - 20 °C

5.1: triethylamine / palladium diacetate; tris-(o-tolyl)phosphine / 16 h / 60 °C / Inert atmosphere

6.1: hydrogen / palladium 10% on activated carbon / ethyl acetate / 4 h / 20 °C / 3102.97 Torr

7.1: sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane / 16 h / 0 - 20 °C

7.2: 20 °C

With pyridine; N-iodo-succinimide; sulfuric acid; hydroxylamine hydrochloride; hydrogen; iodine; sodium tris(acetoxy)borohydride; sodium hydrogencarbonate; triethylamine; potassium iodide; sodium hydroxide; palladium 10% on activated carbon; palladium diacetate; tris-(o-tolyl)phosphine; In tetrahydrofuran; ethanol; water; ethyl acetate; 1,2-dichloro-ethane;

Reference yield:

: 52063-44-2
3-methyl-5-(4-nitrophenyl)isoxazole

: 1356600-57-1
methyl 3-(5-{4-[(4-{[(2E,2Z)-2-(4-cyanophenyl)-2-(methoxyimino)ethyl]oxy}benzyl)amino]phenyl}-3-methyl-1,2-oxazol-4-yl)propanoate

Guidance literature:: Multi-step reaction with 4 steps

1.1: sulfuric acid; N-iodo-succinimide / 1,2-dichloro-ethane / 4 h / 0 - 20 °C

2.1: triethylamine / palladium diacetate; tris-(o-tolyl)phosphine / 16 h / 60 °C / Inert atmosphere

3.1: hydrogen / palladium 10% on activated carbon / ethyl acetate / 4 h / 20 °C / 3102.97 Torr

4.1: sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane / 16 h / 0 - 20 °C

4.2: 20 °C

With N-iodo-succinimide; sulfuric acid; hydrogen; sodium tris(acetoxy)borohydride; triethylamine; palladium 10% on activated carbon; palladium diacetate; tris-(o-tolyl)phosphine; In ethyl acetate; 1,2-dichloro-ethane;