2-(2-fluorophenyl)-1-[(3-methylpiperidin-1-yl)sulfonyl]-1H-imidazole-4-carbaldehyde

Base Information

Chemical Name:2-(2-fluorophenyl)-1-[(3-methylpiperidin-1-yl)sulfonyl]-1H-imidazole-4-carbaldehyde
CAS No.:1138036-41-5
Molecular Formula:C₁₆H₁₈FN₃O₃S
Molecular Weight:351.402
Hs Code.:

Synonyms:2-(2-fluorophenyl)-1-[(3-methylpiperidin-1-yl)sulfonyl]-1H-imidazole-4-carbaldehyde

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(2-fluorophenyl)-1-[(3-methylpiperidin-1-yl)sulfonyl]-1H-imidazole-4-carbaldehyde

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Technology Process of 2-(2-fluorophenyl)-1-[(3-methylpiperidin-1-yl)sulfonyl]-1H-imidazole-4-carbaldehyde

There total 1 articles about 2-(2-fluorophenyl)-1-[(3-methylpiperidin-1-yl)sulfonyl]-1H-imidazole-4-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 627887-46-1
3-methylpiperidine-1-sulfonyl chloride

: 1138033-98-3
2-(2-fluorophenyl)-1H-imidazole-4-carbaldehyde

: 1138036-41-5
2-(2-fluorophenyl)-1-[(3-methylpiperidin-1-yl)sulfonyl]-1H-imidazole-4-carbaldehyde

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

Reference yield: 15.0%

: 1138036-41-5
2-(2-fluorophenyl)-1-[(3-methylpiperidin-1-yl)sulfonyl]-1H-imidazole-4-carbaldehyde

: 593-51-1
methylamine hydrochloride

: 110-17-8,26099-09-2
(2E)-but-2-enedioic acid

: 1-{2-(2-fluorophenyl)-1-[(3-methylpiperidin-1-yl)sulfonyl]-1H-imidazol-4-yl}-N-methylmethanamine 1.5 fumarate

Guidance literature:: 2-(2-fluorophenyl)-1-[(3-methylpiperidin-1-yl)sulfonyl]-1H-imidazole-4-carbaldehyde; methylamine hydrochloride; In methanol; for 0.0833333h;

With methanol; sodium tris(acetoxy)borohydride; for 1h;

(2E)-but-2-enedioic acid; In methanol; ethyl acetate;