Technology Process of N-(2-iodophenyl)-2-phenylacrylamide
There total 6 articles about N-(2-iodophenyl)-2-phenylacrylamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dmap; triethylamine;
In
dichloromethane;
at -20 - 20 ℃;
Inert atmosphere;
DOI:10.1021/ol402210a
- Guidance literature:
-
Multi-step reaction with 2 steps
1: thionyl chloride / 0.5 h / 80 °C
2: dmap; triethylamine / dichloromethane / -20 - 20 °C / Inert atmosphere
With
dmap; thionyl chloride; triethylamine;
In
dichloromethane;
DOI:10.1021/ol402210a
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium carbonate; tetra-(n-butyl)ammonium iodide / toluene / 12 h / 70 °C
2: potassium hydroxide / tetrahydrofuran; water / 2 h / Reflux
3: oxalyl dichloride / N,N-dimethyl-formamide; dichloromethane / 2 h / 0 - 20 °C
4: triethylamine / dichloromethane / 6 h / 0 - 20 °C
With
oxalyl dichloride; tetra-(n-butyl)ammonium iodide; potassium carbonate; triethylamine; potassium hydroxide;
In
tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; toluene;
DOI:10.1039/c7cc06196j
