Povidone iodine

Base Information

• Chemical Name: Povidone iodine
• CAS No.: 25655-41-8
• Molecular Formula: (C6H9NO)x. xI2
• Molecular Weight: 364.95100
• Hs Code.: 29339900
• European Community (EC) Number: 607-771-8,918-309-2,924-458-4
• ICSC Number: 1471
• NSC Number: 26245,28655
• Wikipedia: Povidone-iodine
• Wikidata: Q241516
• NCI Thesaurus Code: C766
• RXCUI: 8611
• Mol file: 25655-41-8.mol

Synonyms:Alphadine;Alphadines;Betadine;Betadines;Betaisodona;Disadine;Disadines;Isodine;Isodines;Pharmadine;Pharmadines;Polyvinylpyrrolidone Iodine;Polyvinylpyrrolidone Iodines;Povidone Iodine;Povidone-Iodine;Povidone-Iodines;Providine;Providines;PVP Iodine;PVP-I;PVP-Iodine;PVP-Iodines

Chemical Property of Povidone iodine

Chemical Property:

• Appearance/Colour: A red-brown crystalline powder
• Vapor Pressure: 0.132mmHg at 25°C
• Melting Point: 300oC
• Boiling Point: 217.6oC at 760 mmHg
• Flash Point: 93.9oC
• PSA: 20.31000
• LogP: 2.46160
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: H2O: soluble100mg/mL
• Water Solubility.: Soluble in water, ethyl alcohol, isopropyl alcohol, polyethylene glycol and glycerol. Insoluble in chloroform, carbon tetrachlor
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 364.87736
• Heavy Atom Count: 10
• Complexity: 120

Purity/Quality:

99% ^*data from raw suppliers

Povidone-iodine ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25-22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Uses -> Biocides/Disinfectants
• Canonical SMILES: C=CN1CCCC1=O.II
• Recent ClinicalTrials: Chlorhexidine and/or Betadine Prep in Pediatric Arm Surgery Following Trauma
• Recent EU Clinical Trials: Prospective Randomized Evaluation of Emerging Novel Treatments for Infection prophylaxis in Total Joint Replacement (PREVENT-iT): A Pilot Study
• Effects of Long Term Exposure: Repeated or prolonged contact with skin may cause dermatitis.
• Discovery of Povidone-Iodine: Povidone-iodine was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V.
• Preparation Method: The preparation method involves mixing polyvinylpyrrolidone K with iodine. The steps include adding iodine and polyvinylpyrrolidone K30 into a solid-phase reactor, sealing the cover, rotating the reactor, heating, and continuous rotation until cooled.
• Chemical Composition and Characteristics: Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It is a loose complex composed of elemental iodine and a polymer carrier, povidone, which acts as a dissolution aid. The available iodine content in povidone-iodine should be within the range of 9.0% to 12.0%.
• Identification and Use: Povidone-iodine is identified by its characteristic reactions, such as forming a dark blue color when mixed with starch indicator solution and producing a brown, dry film when applied on a glass plate and dried overnight. It is used as a broad-spectrum, powerful bactericidal disinfectant effective against viruses, bacteria, fungi, and mold spores.; Povidone-iodine has little irritation to the skin, low toxicity, and long-lasting effects, making it safe and easy to use. It is commonly used for skin and mucous membrane disinfection, including cleaning before surgery, disinfecting surgical sites, and treating wounds.
• Application in Veterinary Medicine: Povidone-iodine, usually formulated as a 10% solution, is used as a disinfectant in veterinary medicine. It effectively kills various pathogens in animals, including viruses (Newcastle disease, avian influenza), bacteria (E. coli, salmonella), and parasites (livestock and poultry parasites' eggs). Additionally, it can inhibit the breeding of insects like mosquitoes and flies and can be used in fruit trees, crops, fish, and shrimp farming.