5-Methoxy-2,3,3-trimethylindolenine

Base Information

• Chemical Name: 5-Methoxy-2,3,3-trimethylindolenine
• CAS No.: 41382-23-4
• Molecular Formula: C₁₂H₁₇NO
• Molecular Weight: 191.273
• Hs Code.: 2933990090
• Mol file: 41382-23-4.mol

Synonyms:2,3,3-Trimethyl-5-methoxyindoline;5-Methoxy-2,3,3-trimethylindoline

Chemical Property of 5-Methoxy-2,3,3-trimethylindolenine

Chemical Property:

• Vapor Pressure: 0.00187mmHg at 25°C
• Boiling Point: 292 ºC
• Flash Point: 118 ºC
• PSA: 21.26000
• Density: 0.971
• LogP: 2.92480

Purity/Quality:

98%min ^*data from raw suppliers

5-METHOXY-2,3,3-TRIMETHYLINDOLINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Methoxy-2,3,3-trimethylindolenine

There total 4 articles about 5-Methoxy-2,3,3-trimethylindolenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-Methoxy-2,3,3-trimethyl-3H-indole (31241-19-7) → 5-Methoxy-2,3,3-trimethylindolin (41382-23-4)

Guidance literature:

With sodium tetrahydroborate; In methanol; water; at 0 - 20 ℃; for 3h; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.201302140

Reference yield:

4-methoxyphenylhydrazine hydrochloride (19501-58-7) → 5-Methoxy-2,3,3-trimethylindolin (41382-23-4)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / 14 h / 120 °C / Inert atmosphere; Schlenk technique

2: sodium tetrahydroborate / methanol; water / 3 h / 0 - 20 °C / Inert atmosphere; Schlenk technique

With sodium tetrahydroborate; acetic acid; In methanol; water;

DOI:10.1002/chem.201302140

Reference yield:

3-methyl-butan-2-one (563-80-4) → 5-Methoxy-2,3,3-trimethylindolin (41382-23-4)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / 14 h / 120 °C / Inert atmosphere; Schlenk technique

2: sodium tetrahydroborate / methanol; water / 3 h / 0 - 20 °C / Inert atmosphere; Schlenk technique

With sodium tetrahydroborate; acetic acid; In methanol; water;

DOI:10.1002/chem.201302140

upstream raw materials:

4-methoxyphenylhydrazine hydrochloride

3-methyl-butan-2-one

5-Methoxy-2,3,3-trimethyl-3H-indole

Refernces