(1R,2S)-2-(p-tolylsulfonylamino)-1-phenylpropyl (S)-2-(N,N-dimethylamino)phenyl sulfinate

Base Information

Chemical Name:(1R,2S)-2-(p-tolylsulfonylamino)-1-phenylpropyl (S)-2-(N,N-dimethylamino)phenyl sulfinate
CAS No.:642473-02-7
Molecular Formula:C₂₄H₂₈N₂O₄S₂
Molecular Weight:472.629
Hs Code.:

Synonyms:(1R,2S)-2-(p-tolylsulfonylamino)-1-phenylpropyl (S)-2-(N,N-dimethylamino)phenyl sulfinate

Suppliers and Price of (1R,2S)-2-(p-tolylsulfonylamino)-1-phenylpropyl (S)-2-(N,N-dimethylamino)phenyl sulfinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,2S)-2-(p-tolylsulfonylamino)-1-phenylpropyl (S)-2-(N,N-dimethylamino)phenyl sulfinate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,2S)-2-(p-tolylsulfonylamino)-1-phenylpropyl (S)-2-(N,N-dimethylamino)phenyl sulfinate

There total 1 articles about (1R,2S)-2-(p-tolylsulfonylamino)-1-phenylpropyl (S)-2-(N,N-dimethylamino)phenyl sulfinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 698-02-2
N,N-dimethyl-o-iodoaniline

: 473554-15-3
(2R,4S,5R)-4-methyl-5-phenyl-3-(toluene-4-sulfonyl)oxathiazolidine-2-oxide

: 642473-02-7
(1R,2S)-2-(p-tolylsulfonylamino)-1-phenylpropyl (S)-2-(N,N-dimethylamino)phenyl sulfinate

Guidance literature:: N,N-dimethyl-o-iodoaniline; With iodine; magnesium; In diethyl ether; Heating;

(2R,4S,5R)-4-methyl-5-phenyl-3-(toluene-4-sulfonyl)oxathiazolidine-2-oxide; In tetrahydrofuran; diethyl ether; at -78 ℃; for 1h;
DOI:10.1021/ja038491l

Reference yield: 66.0%

: 1826-67-1
vinyl magnesium bromide

: 642473-02-7
(1R,2S)-2-(p-tolylsulfonylamino)-1-phenylpropyl (S)-2-(N,N-dimethylamino)phenyl sulfinate

: 642472-93-3
(R)-2-(N,N-dimethylamino)phenyl vinyl sulfoxide

Guidance literature:: In tetrahydrofuran; at -78 ℃; for 2h;
DOI:10.1021/ja038491l DOI:10.1002/chem.200400443

Reference yield:

: 642473-02-7
(1R,2S)-2-(p-tolylsulfonylamino)-1-phenylpropyl (S)-2-(N,N-dimethylamino)phenyl sulfinate

: 642473-03-8
(5S,S_R)-5-[2-(N,N-dimethylamino)phenylsulfinyl]-2-(triisopropylsilyloxy)methyl-2-cyclopentenone

Guidance literature:: Multi-step reaction with 2 steps

1.1: 66 percent / tetrahydrofuran / 2 h / -78 °C

2.2: N-methylmorpholine N-oxide*H₂O / acetonitrile

In tetrahydrofuran; 2.2: intermolecular Pauson-Khand reaction;
DOI:10.1002/chem.200400443