Arsenic

Base Information

• Chemical Name: Arsenic
• CAS No.: 7440-38-2
• Molecular Formula: AsH₃
• Molecular Weight: 77.9454
• Hs Code.: 2804800000
• European Community (EC) Number: 231-148-6
• ICSC Number: 0013
• UN Number: 1558,1562
• UNII: V1I29R0RJQ
• DSSTox Substance ID: DTXSID3023760,DTXSID501080836,DTXSID201080837
• Wikipedia: Arsenic
• Wikidata: Q871
• NCI Thesaurus Code: C28131
• ChEMBL ID: CHEMBL1231052
• Mol file: 7440-38-2.mol

Synonyms:7440-38-2;Arsenic;As;Agent SA;Arsenic-75;Arsenowodor;Arsenicals;Arsen;Arsenwasserstoff;Gray arsenic;Grey arsenic;Arsenic Black;Metallic arsenic;Colloidal arsenic;Arsenic hydride (AsH3);Arsenic, inorganic;Arsenowodor [Polish];ARSENIC METAL;Arsenwasserstoff [German];CCRIS 55;Arsenic, elemental;HSDB 509;HSDB 510;Arsen [German,Polish];EINECS 231-148-6;EINECS 232-066-3;UN2188;UNII-V1I29R0RJQ;UN 2188;V1I29R0RJQ;UNII-N712M78A8G;CHEBI:27563;UN1558;EC 232-066-3;Arsenic 75;arsenico;arsenicum;Arsenamina;Arsenhydrid;Arsinidene;Arsina;arsenic atom;Arsin;Arsenic sponge;Arsine Gas;Inorganic arsenic;Arsine (DOT;Arsenic (Inorganic);ARSINO;ARSENIC, SOLID;ARX (CHRIS Code);ARSENIC, METALLIC;As-H3;ARSINE [MI];ARSENIC, (SOLID);ARSENICUM METALLICUM;33As;ARSENIC METAL: ARSENIA;DTXCID703886;Arsenic [UN1558] [Poison];CHEMBL1231052;DTXSID3023760;DTXSID4023886;CHEBI:35826;RQNWIZPPADIBDY-UHFFFAOYSA-N;DTXSID201080837;DTXSID501080836;N712M78A8G;Arsenic, >=99.999%, pieces;Arsine [UN2188] [Poison gas];Arsine [UN2188] [Poison gas];NA1558;NA2188;AKOS015902733;LS-1736;Arsenic, 99.999% trace metals basis;LS-21723;FT-0696579;C06269;Arsenic, powder, >=99.997% trace metals basis;ARSENIC AND INORGANIC ARSENIC COMPOUNDS (IARC);Q21060492

Chemical Property of Arsenic

Chemical Property:

• Appearance/Colour: Grey powder or chunks
• Vapor Pressure: 10600mmHg at 25°C
• Melting Point: 817 °C(lit.)
• Boiling Point: 613 °C(lit.)
• PSA: 0.00000
• Density: 5.727 g/cm³
• LogP: -0.04330
• Water Solubility.: insoluble
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 74.921595
• Heavy Atom Count: 1
• Complexity: 0
• Transport DOT Label: Poison

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s): T,N
• Hazard Codes: T:Toxic;;
• Statements: R23/25:; R50/53:
• Safety Statements: S20/21:; S28:; S45:; S60:; S61:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Metals -> Arsenic Compounds, Inorganic
• Drug Classes: Trace Elements and Metals
• Canonical SMILES: [As]
• Recent ClinicalTrials: A Study Comparing the Effects and Safety of Dulaglutide With Glimepiride in Type 2 Diabetes Mellitus
• Recent NIPH Clinical Trials: Post remission therapy including arsenic trioxide against acute promylocytic leukemia (APL) in elderly patients. (JALSG APL212G study)
• Inhalation Risk: A harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered.
• Effects of Short Term Exposure: The substance may cause effects on the gastrointestinal tract. This may result in severe gastroenteritis, loss of fluids and electrolytes, cardiac disorders, shock and convulsions. Exposure far above the OEL could cause death. The effects may be delayed. Medical observation is indicated.
• Effects of Long Term Exposure: The substance may have effects on the skin, mucous membranes, peripheral nervous system, liver and bone marrow. This may result in pigmentation disorders, hyperkeratosis, perforation of the nasal septum, neuropathy, anaemia and liver impairment. This substance is carcinogenic to humans. Animal tests show that this substance possibly causes toxicity to human reproduction or development.

Technology Process of Arsenic

There total 163 articles about Arsenic which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

arsenic(III) trioxide → arsenic + arsenic (7440-38-2,460345-38-4,7784-42-1,127323-69-7)

Guidance literature:

In sulfuric acid; aq. H2SO4; Electrolysis; prepn. by galvanostatic electrolysis of satd. soln. of As2O3 in 10% H2SO4 at 25-30°C and cathode current density of 0.3 A/cm**2; durationof each run was 1 h, while bubbling the soln. with Ar; lead was used as cathode;

DOI:10.1134/S0020168507010074

Reference yield: 65.3%

orthoarsenic acid (7778-39-4,121471-47-4,1327-52-2) → arsenic (7440-38-2,460345-38-4,7784-42-1,127323-69-7)

Guidance literature:

In water; byproducts: As; Electrolysis; Pt anode; ceramic or cation-exchange membrane; Cd, Cu, stainless steel, Sn, Ti, Ni, Pb cathode; j = 0.1-0.2 A/cm**2, at 14-50°C; electrolysis time: 0.5-3.0 h; optimal H3AsO4 concn. is 4-10 mol/l; chem. anal.;

DOI:10.1023/A:1021831017530

Reference yield: 0.67%

calcium arsenide → arsenic (7440-38-2,460345-38-4,7784-42-1,127323-69-7)

Guidance literature:

With water; In water; byproducts: H2; decompn. of Ca3As2 (prepared by burning of Ca-As-quartz sand mixture) in water;; AsH3 contains ca 14 vol.-% H2;;

upstream raw materials:

magnesium

water

arsenic trichloride

sulfuric acid

Downstream raw materials:

hydrogen bromide

orthoarsenic acid

cadmium

sodium arsenide

Refernces

• 1、 Hulley, Elliott B.,Bonanno, Jeffrey B.,Wolczanski, Peter T.,Cundari, Thomas R.,Lobkovsky, Emil B.. "Pnictogen-hydride activation by (silox)3Ta (silox = tBu3SiO); Attempts to circumvent the constraints of orbital symmetry in N2 activation". . p. 8524 - 8544. Retrieved 2010/12/18.
• 2、 Smirnov,Turygin,Shalashova,Khudenko,Tomilov. "Electrochemical reduction of As(III) in acid media". . p. 25 - 29. Retrieved 2008/10/09.