tert-butyl 4-(2-(2-(4-((dimethylamino)methyl)piperidin-1-yl)phenylcarbamoyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)pyridin-2-ylcarbamate

Base Information

Chemical Name:tert-butyl 4-(2-(2-(4-((dimethylamino)methyl)piperidin-1-yl)phenylcarbamoyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)pyridin-2-ylcarbamate
CAS No.:1350918-13-6
Molecular Formula:C₃₄H₅₁N₇O₄Si
Molecular Weight:649.909
Hs Code.:

tert-butyl 4-(2-(2-(4-((dimethylamino)methyl)piperidin-1-yl)phenylcarbamoyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)pyridin-2-ylcarbamate

Synonyms:tert-butyl 4-(2-(2-(4-((dimethylamino)methyl)piperidin-1-yl)phenylcarbamoyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)pyridin-2-ylcarbamate

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Chemical Property of tert-butyl 4-(2-(2-(4-((dimethylamino)methyl)piperidin-1-yl)phenylcarbamoyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)pyridin-2-ylcarbamate

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Technology Process of tert-butyl 4-(2-(2-(4-((dimethylamino)methyl)piperidin-1-yl)phenylcarbamoyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)pyridin-2-ylcarbamate

There total 1 articles about tert-butyl 4-(2-(2-(4-((dimethylamino)methyl)piperidin-1-yl)phenylcarbamoyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)pyridin-2-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 1095708-32-9
N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]carbamic acid 1,1-dimethylethyl ester

: 1350918-12-5
C₂₄H₃₈BrN₅O₂Si

: 1350918-13-6
tert-butyl 4-(2-(2-(4-((dimethylamino)methyl)piperidin-1-yl)phenylcarbamoyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)pyridin-2-ylcarbamate

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; water; toluene; at 110 ℃; for 1h; Inert atmosphere; Microwave irradiation;

Reference yield: 77.0%

: 1350918-13-6
tert-butyl 4-(2-(2-(4-((dimethylamino)methyl)piperidin-1-yl)phenylcarbamoyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)pyridin-2-ylcarbamate

: 1350916-75-4
4-(2-amino-4-pyridinyl)-N-(2-(4-((dimethylamino)methyl)-1-piperidinyl)phenyl)-1H-imidazole-2-carboxamide

Guidance literature:: tert-butyl 4-(2-(2-(4-((dimethylamino)methyl)piperidin-1-yl)phenylcarbamoyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)pyridin-2-ylcarbamate; With hydrogenchloride; In 1,4-dioxane; methanol; at 50 ℃; for 2h;

With ammonia; In methanol; dichloromethane;