2-Chloro-3-methoxyaniline

Base Information

Chemical Name:2-Chloro-3-methoxyaniline
CAS No.:113206-03-4
Molecular Formula:C7H8ClNO
Molecular Weight:157.6
Hs Code.:2922299090
Mol file:113206-03-4.mol

Synonyms:(2-Chloro-3-methoxyphenyl)amine;

Suppliers and Price of 2-Chloro-3-methoxyaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-3-methoxyaniline
25g
$ 745.00

TRC
2-Chloro-3-methoxyaniline
10g
$ 320.00

TRC
2-Chloro-3-methoxyaniline
1g
$ 85.00

Matrix Scientific
2-Chloro-3-methoxyaniline 95+%
1g
$ 51.00

Matrix Scientific
2-Chloro-3-methoxyaniline 95+%
5g
$ 153.00

Matrix Scientific
2-Chloro-3-methoxyaniline 95+%
10g
$ 247.00

Crysdot
2-Chloro-3-methoxyaniline 98%
100g
$ 970.00

Crysdot
2-Chloro-3-methoxyaniline 98%
25g
$ 287.00

Chemenu
2-Chloro-3-methoxyaniline 95+%
5g
$ 70.00

Biosynth Carbosynth
2-Chloro-3-methoxyaniline
25 g
$ 420.00

Total 61 raw suppliers

Chemical Property of 2-Chloro-3-methoxyaniline

Chemical Property:

Appearance/Colour:Kind of white to yellow powder
Vapor Pressure:0.00191mmHg at 25°C
Melting Point:50 °C
Boiling Point:252 °C at 760 mmHg
PKA:2.23±0.10(Predicted)
Flash Point:106.2 °C
PSA：35.25000
Density:1.234 g/cm³
LogP:2.51200
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

99%, ^*data from raw suppliers

2-Chloro-3-methoxyaniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2-Chloro-3-methoxyaniline is a reactant used in the preparation of dual inhibitors of CK2 and Pim kinases with antiproliferative activity against cancer cells.

Technology Process of 2-Chloro-3-methoxyaniline

There total 4 articles about 2-Chloro-3-methoxyaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 3970-39-6
2-chloro-3-methoxynitrobenzene

: 113206-03-4
2-chloro-3-methoxyphenylamine

Guidance literature:: With iron; acetic acid; In ethanol; for 3.5h; Heating / reflux;

Reference yield:

: 1073118-74-7
C₁₂H₁₆ClNO₃

: 113206-03-4
2-chloro-3-methoxyphenylamine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃;
DOI:10.1016/j.bmcl.2008.07.088 DOI:10.1016/j.bmcl.2008.07.124

Reference yield:

: 16554-45-3
2-methoxy-6-nitroaniline

: 113206-03-4
2-chloro-3-methoxyphenylamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium nitrite; hydrogenchloride / water; acetonitrile / 0.25 h / 20 °C

1.2: 3 h / 60 °C

2.1: ammonium chloride; iron / water; ethanol / 12 h / 95 °C

With hydrogenchloride; iron; ammonium chloride; sodium nitrite; In ethanol; water; acetonitrile;
DOI:10.1002/chem.201701707