Technology Process of 3-(4-methoxy-2-nitrophenyl)propan-1-ol
There total 6 articles about 3-(4-methoxy-2-nitrophenyl)propan-1-ol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(E)-4-methoxy-2-nitrocinnamyl alcohol;
With
lithium borohydride;
In
tetrahydrofuran;
at 0 - 20 ℃;
With
water; ammonium chloride;
In
tetrahydrofuran;
at 0 ℃;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: water; sodium hydrogencarbonate / 22 h / Heating / reflux
2.1: pyridine / piperidine / 12 h / 125 °C
3.1: thionyl chloride / 3 h / 0 °C / Heating / reflux
4.1: diisobutylaluminium hydride / toluene / 3 h / 0 - 20 °C
5.1: lithium borohydride / tetrahydrofuran / 0 - 20 °C
5.2: 0 °C
With
pyridine; lithium borohydride; thionyl chloride; water; diisobutylaluminium hydride; sodium hydrogencarbonate;
piperidine;
In
tetrahydrofuran; toluene;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 24 h / 80 °C
2.1: water; sodium hydrogencarbonate / 22 h / Heating / reflux
3.1: pyridine / piperidine / 12 h / 125 °C
4.1: thionyl chloride / 3 h / 0 °C / Heating / reflux
5.1: diisobutylaluminium hydride / toluene / 3 h / 0 - 20 °C
6.1: lithium borohydride / tetrahydrofuran / 0 - 20 °C
6.2: 0 °C
With
pyridine; N-Bromosuccinimide; lithium borohydride; thionyl chloride; water; diisobutylaluminium hydride; sodium hydrogencarbonate; dibenzoyl peroxide;
piperidine;
In
tetrahydrofuran; tetrachloromethane; toluene;
