2-Trifluoromethyl-5-pyridineboric acid

Base Information

Chemical Name:2-Trifluoromethyl-5-pyridineboric acid
CAS No.:868662-36-6
Molecular Formula:C₆H₅BF₃NO₂
Molecular Weight:190.917
Hs Code.:2933399090
Mol file:868662-36-6.mol

Synonyms:3-Trifluoromethyl-4-pyrazolylboric acid;2-Trifluoromethyl-pyridine-5-boronic acid;[6-(Trifluoromethyl)-3-pyridyl]boronic acid;6-Trifluoromethylpyridine-3-boronic acid;

Suppliers and Price of 2-Trifluoromethyl-5-pyridineboric acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
2-Trifluoromethylpyridine-5-boronicacid
1g
$ 87.00

Alfa Aesar
2-(Trifluoromethyl)pyridine-5-boronic acid, 98%
1g
$ 96.80

Alfa Aesar
2-(Trifluoromethyl)pyridine-5-boronic acid, 98%
250mg
$ 30.40

Alfa Aesar
2-(Trifluoromethyl)pyridine-5-boronic acid, 98%
5g
$ 346.00

Alichem
(6-(Trifluoromethyl)pyridin-3-yl)boronicacid
25g
$ 353.50

Alichem
(6-(Trifluoromethyl)pyridin-3-yl)boronicacid
10g
$ 192.40

Ambeed
(6-(Trifluoromethyl)pyridin-3-yl)boronicacid 98%
25g
$ 368.00

Ambeed
(6-(Trifluoromethyl)pyridin-3-yl)boronicacid 98%
250mg
$ 9.00

Ambeed
(6-(Trifluoromethyl)pyridin-3-yl)boronicacid 98%
1g
$ 20.00

Ambeed
(6-(Trifluoromethyl)pyridin-3-yl)boronicacid 98%
5g
$ 81.00

Total 88 raw suppliers

Chemical Property of 2-Trifluoromethyl-5-pyridineboric acid

Chemical Property:

Appearance/Colour:off-white powder
Vapor Pressure:2.85E-06mmHg at 25°C
Refractive Index:1.455
Boiling Point:274.9 °C at 760 mmHg
PKA:6.12±0.10(Predicted)
Flash Point:120.1 °C
PSA：53.35000
Density:1.44 g/cm³
LogP:-0.21980
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Water Solubility.:Slightly soluble in water.

Purity/Quality:

99%,98%, ^*data from raw suppliers

2-Trifluoromethylpyridine-5-boronicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Uses (6-Trifluoromethyl-3-pyridyl)boronic Acid is used for preparation of [[(aryl)heteroaryl]methoxy]nitroimidazooxazines and study of their antituberculosis structure-activity relationship.

Technology Process of 2-Trifluoromethyl-5-pyridineboric acid

There total 5 articles about 2-Trifluoromethyl-5-pyridineboric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.7%

: 5419-55-6
Triisopropyl borate

: 436799-32-5
5-bromo-2(trifluoromethyl)pyridine

: 868662-36-6
6-(trifluoromethyl)-3-pyridinylboronic acid

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 2h; Inert atmosphere;

Reference yield: 95.0%

: 436799-32-5
5-bromo-2(trifluoromethyl)pyridine

: 868662-36-6
6-(trifluoromethyl)-3-pyridinylboronic acid

Guidance literature:: 5-bromo-2(trifluoromethyl)pyridine; With n-butyllithium; Triisopropyl borate; In tetrahydrofuran; hexane; at -78 ℃; for 3h; Inert atmosphere;

With water; In tetrahydrofuran; hexane; at -10 ℃;
DOI:10.1039/b901024f

Reference yield: 95.0%

: 5419-55-6
Triisopropyl borate

: 7732-18-5
water

: 436799-32-5
5-bromo-2(trifluoromethyl)pyridine

: 868662-36-6
6-(trifluoromethyl)-3-pyridinylboronic acid

Guidance literature:: With CH₃CH₂CH₂CH₂Li; In tetrahydrofuran; hexane; addn. of hexane soln. of butyllithium to mixt. of boron compd. and pyridine deriv. in THF at -78°C under Ar, stirring at -78°C for3.5 h, warming to -10°C; addn. of deionized water, evapn., addn. of NaOH to pH 10, washing with diethyl ether, addn. of acetic acid to pH 5, extn. (ethyl acetate), evapn., NMR;
DOI:10.1039/b901024f