(S)-2-[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-3-methyl-heptanoic acid 2,6-di-tert-butyl-4-methoxy-phenyl ester

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Chemical Name:(S)-2-[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-3-methyl-heptanoic acid 2,6-di-tert-butyl-4-methoxy-phenyl ester
CAS No.:141062-28-4
Molecular Formula:C₂₉H₄₈N₂O₄
Molecular Weight:488.711
Hs Code.:

Synonyms:(S)-2-[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-3-methyl-heptanoic acid 2,6-di-tert-butyl-4-methoxy-phenyl ester

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Chemical Property of (S)-2-[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-3-methyl-heptanoic acid 2,6-di-tert-butyl-4-methoxy-phenyl ester

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Technology Process of (S)-2-[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-3-methyl-heptanoic acid 2,6-di-tert-butyl-4-methoxy-phenyl ester

There total 5 articles about (S)-2-[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-3-methyl-heptanoic acid 2,6-di-tert-butyl-4-methoxy-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59983-39-0,187035-29-6
(S)-1-amino-2-(methoxymethyl)pyrrolidine

: 141062-28-4
(S)-2-[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-3-methyl-heptanoic acid 2,6-di-tert-butyl-4-methoxy-phenyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent

2: tBuOK/nBuLi / tetrahydrofuran / -100 - 10 °C / other alkyl halides; enantioselectivity

With n-butyllithium; potassium tert-butylate; In tetrahydrofuran;

Reference yield:

: 489-01-0
2,6-Di-t-butyl-4-methoxyphenol

: 141062-28-4
(S)-2-[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-3-methyl-heptanoic acid 2,6-di-tert-butyl-4-methoxy-phenyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: nBuLi / tetrahydrofuran / 0 °C

2: 98 percent / diethyl ether / -78 °C

3: 96 percent

4: tBuOK/nBuLi / tetrahydrofuran / -100 - 10 °C / other alkyl halides; enantioselectivity

With n-butyllithium; potassium tert-butylate; In tetrahydrofuran; diethyl ether;

Reference yield:

: 141062-26-2
2-Oxo-butyric acid 2,6-di-tert-butyl-4-methoxy-phenyl ester

: 141062-28-4
(S)-2-[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-3-methyl-heptanoic acid 2,6-di-tert-butyl-4-methoxy-phenyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent

2: tBuOK/nBuLi / tetrahydrofuran / -100 - 10 °C / other alkyl halides; enantioselectivity

With n-butyllithium; potassium tert-butylate; In tetrahydrofuran;