<(2'E,4'E)-5'-(2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3'-methyl-2',4'-pentadienyl>triphenylphosphonium chloride

Base Information

• Chemical Name: <(2'E,4'E)-5'-(2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3'-methyl-2',4'-pentadienyl>triphenylphosphonium chloride
• CAS No.: 83020-78-4
• Molecular Formula: C₃₃H₃₆OP*Cl
• Molecular Weight: 515.075
• Mol file: 83020-78-4.mol

Synonyms:<(2'E,4'E)-5'-(2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3'-methyl-2',4'-pentadienyl>triphenylphosphonium chloride

Chemical Property of <(2'E,4'E)-5'-(2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3'-methyl-2',4'-pentadienyl>triphenylphosphonium chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of <(2'E,4'E)-5'-(2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3'-methyl-2',4'-pentadienyl>triphenylphosphonium chloride

There total 8 articles about <(2'E,4'E)-5'-(2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3'-methyl-2',4'-pentadienyl>triphenylphosphonium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7,9,9-trimethyl-1,4-dioxa-spiro[4.5]dec-6-en-8-one (14203-64-6) → <(2'E,4'E)-5'-(2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3'-methyl-2',4'-pentadienyl>triphenylphosphonium chloride (83020-78-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 95.2 percent / NaNH₂, Fe(NO₃)3 / liquid ammonia; toluene / reflux, 2 h then R_.T_. overnight

With sodium amide; ferric nitrate; In ammonia; toluene;

DOI:10.1002/hlca.19820650327

Reference yield:

5-(1-methoxy-1-methylethoxy)-3-methyl-3E-penten-1-yne (80713-62-8) → <(2'E,4'E)-5'-(2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3'-methyl-2',4'-pentadienyl>triphenylphosphonium chloride (83020-78-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 62.0 g / LiNH₂ / liquid ammonia; diethyl ether / 2.5 h / -40 °C

2: 3N H₂SO₄ / acetone / 0.25 h / 0 °C

3: 81.3 percent / Zn, NaCN / propan-1-ol; H₂O / 5 h / Ambient temperature

4: 37percent HCl / CH₂Cl₂ / 0.25 h / 0 °C

5: CH₂Cl₂ / 18 h / Ambient temperature

With hydrogenchloride; lithium amide; sulfuric acid; sodium cyanide; zinc; In propan-1-ol; diethyl ether; dichloromethane; ammonia; water; acetone;

DOI:10.1002/hlca.19820650328

Reference yield:

(1'E,3'E)-4-(5'-hydroxy-3'-methyl-1',3'-pentadienyl)-3,5,5-trimethyl-2-cyclohexen-1-on (83020-77-3) → <(2'E,4'E)-5'-(2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3'-methyl-2',4'-pentadienyl>triphenylphosphonium chloride (83020-78-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 37percent HCl / CH₂Cl₂ / 0.25 h / 0 °C

2: CH₂Cl₂ / 18 h / Ambient temperature

With hydrogenchloride; In dichloromethane;

DOI:10.1002/hlca.19820650328

upstream raw materials:

vinylmagnesium chloride

triphenylphosphine

acetone

4,12,12-trimethyl-1,7,10-trioxadispiro<2.2.4.2>dodec-4-en

Downstream raw materials:

3'-hydroxy-ε,ε-carotene-3-one

3-hydroxy-12'-apo-ε-carotene-12'-al

(3R,6'RS)-3-hydroxy-β,ε-caroten-3'-one

3,3'-di-keto-β-carotene

Refernces

• 1、 -. "Process for the manufacture of cyclohexene derivatives". . . Retrieved 2008/06/13.