phenyl 2,4,6-tri-O-acetyl-3-O-benzyl-1-thio-α-L-idopyranoside

Base Information

• Chemical Name: phenyl 2,4,6-tri-O-acetyl-3-O-benzyl-1-thio-α-L-idopyranoside
• CAS No.: 158325-38-3
• Molecular Formula: C₂₅H₂₈O₈S
• Molecular Weight: 488.559
• Mol file: 158325-38-3.mol

Synonyms:phenyl 2,4,6-tri-O-acetyl-3-O-benzyl-1-thio-α-L-idopyranoside

Chemical Property of phenyl 2,4,6-tri-O-acetyl-3-O-benzyl-1-thio-α-L-idopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenyl 2,4,6-tri-O-acetyl-3-O-benzyl-1-thio-α-L-idopyranoside

There total 2 articles about phenyl 2,4,6-tri-O-acetyl-3-O-benzyl-1-thio-α-L-idopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

thiophenol (108-98-5) + 1,2,4,6-tetra-O-acetyl-3-O-benzyl-L-idopyranoside (118711-49-2) → phenyl 2,4,6-tri-O-acetyl-3-O-benzyl-1-thio-α-L-idopyranoside (158325-38-3)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at 25 ℃; for 2h;

DOI:10.1016/0008-6215(95)00346-0

Reference yield:

C23H26O7S + acetic anhydride (108-24-7) → C20H24O9S (1021490-95-8) + phenyl 2,4,6-tri-O-acetyl-3-O-benzyl-1-thio-α-L-idopyranoside (158325-38-3)

Guidance literature:

In pyridine; at 20 ℃;

DOI:10.1016/j.carres.2007.12.015

Reference yield: 99.0%

phenyl 2,4,6-tri-O-acetyl-3-O-benzyl-1-thio-α-L-idopyranoside (158325-38-3) → phenyl 3-O-benzyl-1-thio-α-L-idopyranoside (175978-39-9)

Guidance literature:

With sodium methylate; In methanol; at 20 ℃;

DOI:10.1016/j.carres.2007.12.015

upstream raw materials:

thiophenol

1,2,4,6-tetra-O-acetyl-3-O-benzyl-L-idopyranoside

acetic anhydride

Downstream raw materials:

phenyl 3-O-benzyl-1-thio-α-L-idopyranoside

phenyl 3-O-benzyl-4,6-O-benzylidene-1-thio-α-L-idopyranoside

phenyl 2-O-acetyl-3-O-benzyl-4,6-O-benzylidene-1-thio-α-L-idopyranoside

3-O-(2-O-acetyl-α-L-idopyranosyl)-2,5-anhydro-1,6-di-O-benzoyl-D-mannitol