2-(4-methylphenyl)-β-hydroxyethyl phenyl sulfide

Base Information

• Chemical Name: 2-(4-methylphenyl)-β-hydroxyethyl phenyl sulfide
• CAS No.: 119135-82-9
• Molecular Formula: C₁₅H₁₆OS
• Molecular Weight: 244.357
• Mol file: 119135-82-9.mol

Synonyms:2-(4-methylphenyl)-β-hydroxyethyl phenyl sulfide

Chemical Property of 2-(4-methylphenyl)-β-hydroxyethyl phenyl sulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-methylphenyl)-β-hydroxyethyl phenyl sulfide

There total 7 articles about 2-(4-methylphenyl)-β-hydroxyethyl phenyl sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1-ethenyl-4-methylbenzene (622-97-9,24936-41-2) + thiophenol (108-98-5) → 2-(4-methylphenyl)-β-hydroxyethyl phenyl sulfide (119135-82-9)

Guidance literature:

With oxygen; silver nitrate; In N,N-dimethyl-formamide; at 20 ℃; for 4h; Green chemistry;

DOI:10.1039/c4ob00776j

Reference yield: 83.0%

1-ethenyl-4-methylbenzene (622-97-9,24936-41-2) + diphenyldisulfane (882-33-7) → 2-(4-methylphenyl)-β-hydroxyethyl phenyl sulfide (119135-82-9)

Guidance literature:

With carbon tetrabromide; water; In dichloromethane; at 20 ℃; for 12h; regioselective reaction; Inert atmosphere; Irradiation; Green chemistry;

DOI:10.1002/adsc.201900140

Reference yield: 65.0%

1-ethenyl-4-methylbenzene (622-97-9,24936-41-2) + diphenyldisulfane (882-33-7) → 2-(p-tolyl)-2-(phenylsulfenyl)ethanol (139058-60-9) + 2-(4-methylphenyl)-β-hydroxyethyl phenyl sulfide (119135-82-9)

Guidance literature:

diphenyldisulfane; With aluminum (III) chloride; zinc; In water; acetonitrile; at 80 ℃; for 2h;

1-ethenyl-4-methylbenzene; In water; acetonitrile; at 80 ℃; for 2.7h;

DOI:10.1016/j.tetlet.2008.09.071

upstream raw materials:

1-ethenyl-4-methylbenzene

thiophenol

(phenylsulfanylmethyl)trimethylsilane

4-methyl-benzaldehyde

Downstream raw materials:

1-(3,4-dimethoxyphenyl)-1-(4-methylphenyl)ethylene