(E)-2,4,4-trimethyl-3-(3'-methyl-1',3'-butadienyl)-2-cyclohexen-1-one

Base Information

• Chemical Name: (E)-2,4,4-trimethyl-3-(3'-methyl-1',3'-butadienyl)-2-cyclohexen-1-one
• CAS No.: 98418-97-4
• Molecular Formula: C₁₄H₂₀O
• Molecular Weight: 204.312
• Mol file: 98418-97-4.mol

Synonyms:(E)-2,4,4-trimethyl-3-(3'-methyl-1',3'-butadienyl)-2-cyclohexen-1-one

Chemical Property of (E)-2,4,4-trimethyl-3-(3'-methyl-1',3'-butadienyl)-2-cyclohexen-1-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-2,4,4-trimethyl-3-(3'-methyl-1',3'-butadienyl)-2-cyclohexen-1-one

There total 3 articles about (E)-2,4,4-trimethyl-3-(3'-methyl-1',3'-butadienyl)-2-cyclohexen-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(E)-2,4,4-trimethyl-3-(3'-methyl-1',3'-butadienyl)-2-cyclohexen-1-ol (122258-63-3) → (E)-2,4,4-trimethyl-3-(3'-methyl-1',3'-butadienyl)-2-cyclohexen-1-one (98418-97-4)

Guidance literature:

With manganese(IV) oxide; In hexane; for 2h; Reflux;

DOI:10.1016/j.tet.2009.09.074

Reference yield:

2,4,4-trimethyl-3-(3-oxobut-1-enyl)cyclohex-2-enyl acetate (74345-31-6) → (E)-2,4,4-trimethyl-3-(3'-methyl-1',3'-butadienyl)-2-cyclohexen-1-one (98418-97-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 99 percent / diethyl ether

2: 97 percent / LiAlH₄ / diethyl ether / 3 h / Ambient temperature

3: 89 percent / MnO₂ / hexane / 15 h / Ambient temperature

With manganese(IV) oxide; lithium aluminium tetrahydride; In diethyl ether; hexane;

DOI:10.1002/hlca.19850680316

Reference yield:

(E)-2,4,4-trimethyl-3-(3'-methyl-1',3'-butadienyl)-2-cyclohexenyl acetate (98418-95-2) → (E)-2,4,4-trimethyl-3-(3'-methyl-1',3'-butadienyl)-2-cyclohexen-1-one (98418-97-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 97 percent / LiAlH₄ / diethyl ether / 3 h / Ambient temperature

2: 89 percent / MnO₂ / hexane / 15 h / Ambient temperature

With manganese(IV) oxide; lithium aluminium tetrahydride; In diethyl ether; hexane;

DOI:10.1002/hlca.19850680316

upstream raw materials:

(E)-2,4,4-trimethyl-3-(3'-methyl-1',3'-butadienyl)-2-cyclohexen-1-ol

2,4,4-trimethyl-3-(3-oxobut-1-enyl)cyclohex-2-enyl acetate

(E)-2,4,4-trimethyl-3-(3'-methyl-1',3'-butadienyl)-2-cyclohexenyl acetate

Downstream raw materials:

trisporin A

trisporin B

2,4,4-trimethyl-3-((1E,3E)-3-methyl-7-oxo-octa-1,3-dienyl)cyclohex-2-enone

C₂₄H₄₂O₂Si