1-(2,2-difluoro-2-deoxy-β-D-ribofuranosyl)-4-(2-propyl-1-oxopentyl)aminopyrimidin-2-one p-toluenesulfonic acid co-crystal

Base Information

Chemical Name:1-(2,2-difluoro-2-deoxy-β-D-ribofuranosyl)-4-(2-propyl-1-oxopentyl)aminopyrimidin-2-one p-toluenesulfonic acid co-crystal
CAS No.:960397-74-4
Molecular Formula:C₇H₈O₃S*C₁₇H₂₅F₂N₃O₅
Molecular Weight:561.604
Hs Code.:

Synonyms:1-(2,2-difluoro-2-deoxy-β-D-ribofuranosyl)-4-(2-propyl-1-oxopentyl)aminopyrimidin-2-one p-toluenesulfonic acid co-crystal

Suppliers and Price of 1-(2,2-difluoro-2-deoxy-β-D-ribofuranosyl)-4-(2-propyl-1-oxopentyl)aminopyrimidin-2-one p-toluenesulfonic acid co-crystal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(2,2-difluoro-2-deoxy-β-D-ribofuranosyl)-4-(2-propyl-1-oxopentyl)aminopyrimidin-2-one p-toluenesulfonic acid co-crystal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(2,2-difluoro-2-deoxy-β-D-ribofuranosyl)-4-(2-propyl-1-oxopentyl)aminopyrimidin-2-one p-toluenesulfonic acid co-crystal

There total 3 articles about 1-(2,2-difluoro-2-deoxy-β-D-ribofuranosyl)-4-(2-propyl-1-oxopentyl)aminopyrimidin-2-one p-toluenesulfonic acid co-crystal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 892128-60-8
N-(1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)-2-propylpentanamide

: 104-15-4
toluene-4-sulfonic acid

: 960397-74-4
1-(2,2-difluoro-2-deoxy-β-D-ribofuranosyl)-4-(2-propyl-1-oxopentyl)aminopyrimidin-2-one p-toluenesulfonic acid co-crystal

Guidance literature:: In Isopropyl acetate; at 20 ℃; for 0.166667h;

Reference yield:

: C₁₁H₁₈N₂O₂

: 960397-74-4
1-(2,2-difluoro-2-deoxy-β-D-ribofuranosyl)-4-(2-propyl-1-oxopentyl)aminopyrimidin-2-one p-toluenesulfonic acid co-crystal

Guidance literature:: Multi-step reaction with 2 steps

1.1: chloro-trimethyl-silane / pyridine / 2 h / 0 °C

1.2: 0 - 45 °C

1.3: 0 - 45 °C

2.1: Isopropyl acetate / 0.17 h / 20 °C

With chloro-trimethyl-silane; In pyridine; Isopropyl acetate;

Reference yield:

: 99-66-1
valproic acid

: 960397-74-4
1-(2,2-difluoro-2-deoxy-β-D-ribofuranosyl)-4-(2-propyl-1-oxopentyl)aminopyrimidin-2-one p-toluenesulfonic acid co-crystal

Guidance literature:: Multi-step reaction with 3 steps

1.1: chloro-trimethyl-silane / acetonitrile / 2.5 h

1.3: 0 - 45 °C

2.1: chloro-trimethyl-silane / pyridine / 2 h / 0 °C

2.2: 0 - 45 °C

2.3: 0 - 45 °C

3.1: Isopropyl acetate / 0.17 h / 20 °C

With chloro-trimethyl-silane; In pyridine; Isopropyl acetate; acetonitrile;