Boc-N-methyl-L-valine

Base Information

Chemical Name:Boc-N-methyl-L-valine
CAS No.:45170-31-8
Molecular Formula:C11H21NO4
Molecular Weight:231.292
Hs Code.:29225090
DSSTox Substance ID:DTXSID10426676
Nikkaji Number:J795.975C
Wikidata:Q72450088
Mol file:45170-31-8.mol

Synonyms:Boc-N-Me-Val-OH;N-tert-Butoxycarbonyl-N-methyl-L-valine;N-tert-Butoxycarbonyl-N-methylvaline;

Suppliers and Price of Boc-N-methyl-L-valine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Boc-N-methyl-L-valine
500mg
$ 333.00

Usbiological
Boc-N-methyl-L-valine
1g
$ 219.00

TRC
N-Boc-N-methyl-L-valine
1g
$ 45.00

Sigma-Aldrich
Boc-N-Me-Val-OH Novabiochem?
5 g
$ 107.00

Sigma-Aldrich
Boc-N-Me-Val-OH Novabiochem . CAS 45170-31-8, molar mass 231.29 g/mol., Novabiochem
8530850005
$ 103.00

Sigma-Aldrich
Boc-N-Me-Val-OH ≥99.0% (TLC)
1g
$ 72.00

Matrix Scientific
Boc-Nalpha-methyl-L-valine
5g
$ 198.00

Matrix Scientific
Boc-Nalpha-methyl-L-valine
1g
$ 52.00

Crysdot
Boc-N-Me-Val-OH 97%
500g
$ 1268.00

Crysdot
Boc-N-Me-Val-OH 97%
100g
$ 416.00

Total 93 raw suppliers

Chemical Property of Boc-N-methyl-L-valine

Chemical Property:

Appearance/Colour:White powder
Vapor Pressure:5.74E-05mmHg at 25°C
Melting Point:52.9oC (dec.)
Refractive Index:1.466
Boiling Point:322.4 °C at 760 mmHg
PKA:4.03±0.10(Predicted)
Flash Point:148.8 °C
PSA：66.84000
Density:1.069 g/cm³
LogP:1.96250
Storage Temp.:Store at RT.
Solubility.:Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:231.14705815
Heavy Atom Count:16
Complexity:268

Purity/Quality:

98% ^*data from raw suppliers

Boc-N-methyl-L-valine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(C(=O)O)N(C)C(=O)OC(C)(C)C
Isomeric SMILES:CC(C)[C@@H](C(=O)O)N(C)C(=O)OC(C)(C)C
Recent ClinicalTrials:Safety and Efficacy Study of Q301 in Mild to Moderate Adolescents and Adults Atopic Dermatitis Patients
Uses N-Boc-N-methyl-L-valine is an amino acid derived compound that functions as a useful pharmaceutical intermediate and also employed as a reagent used in organic synthesis. It is used in the synthesis of lactam analog of actinomycin D, a potential antitumor chemotherapeutic agent.

Technology Process of Boc-N-methyl-L-valine

There total 17 articles about Boc-N-methyl-L-valine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 22838-58-0
Boc-D-Val-OH

: 74-88-4
methyl iodide

: 13850-91-4,45170-31-8,89536-85-6
(R)-2-(tert-butoxycarbonyl(methyl)amino)-3-methylbutanoic acid

Guidance literature:: Boc-D-Val-OH; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 0.5h; Inert atmosphere;

methyl iodide; In tetrahydrofuran; mineral oil; at 20 ℃; for 36h; Inert atmosphere;
DOI:10.1039/c5ob02505b