2-{3-[3-(2-Methoxy-phenoxy)-propylamino]-propyl}-2-(3,4,5-trimethoxy-phenyl)-octanenitrile

Base Information

Chemical Name:2-{3-[3-(2-Methoxy-phenoxy)-propylamino]-propyl}-2-(3,4,5-trimethoxy-phenyl)-octanenitrile
CAS No.:108781-09-5
Molecular Formula:C₃₀H₄₄N₂O₅
Molecular Weight:512.69
Hs Code.:

Synonyms:2-{3-[3-(2-Methoxy-phenoxy)-propylamino]-propyl}-2-(3,4,5-trimethoxy-phenyl)-octanenitrile

Suppliers and Price of 2-{3-[3-(2-Methoxy-phenoxy)-propylamino]-propyl}-2-(3,4,5-trimethoxy-phenyl)-octanenitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-{3-[3-(2-Methoxy-phenoxy)-propylamino]-propyl}-2-(3,4,5-trimethoxy-phenyl)-octanenitrile

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-{3-[3-(2-Methoxy-phenoxy)-propylamino]-propyl}-2-(3,4,5-trimethoxy-phenyl)-octanenitrile

There total 6 articles about 2-{3-[3-(2-Methoxy-phenoxy)-propylamino]-propyl}-2-(3,4,5-trimethoxy-phenyl)-octanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13338-63-1
2-(3,4,5-trimethoxyphenyl)acetonitrile

: 108781-09-5
2-{3-[3-(2-Methoxy-phenoxy)-propylamino]-propyl}-2-(3,4,5-trimethoxy-phenyl)-octanenitrile

Guidance literature:: Multi-step reaction with 6 steps

1: 105.00 g / NaOEt / ethanol / 120 - 140 °C

2: ethanol / 1 h / Heating

3: NaOH / H₂O; methanol / 2 h / Heating

4: 1.) NaNH₂

5: aq. (COOH)2

6: 2.) NaBH₄ / 1.) EtOH, 1.5 h, reflux, 2.) EtOH, ice water, 1 h, room temp.

With sodium hydroxide; sodium tetrahydroborate; sodium ethanolate; oxalic acid; sodium amide; In methanol; ethanol; water;
DOI:10.1248/cpb.36.373

Reference yield:

: α-cyano-3,4,5-trimethoxybenzeneacetate sodium salt

: 108781-09-5
2-{3-[3-(2-Methoxy-phenoxy)-propylamino]-propyl}-2-(3,4,5-trimethoxy-phenyl)-octanenitrile

Guidance literature:: Multi-step reaction with 5 steps

1: ethanol / 1 h / Heating

2: NaOH / H₂O; methanol / 2 h / Heating

3: 1.) NaNH₂

4: aq. (COOH)2

5: 2.) NaBH₄ / 1.) EtOH, 1.5 h, reflux, 2.) EtOH, ice water, 1 h, room temp.

With sodium hydroxide; sodium tetrahydroborate; oxalic acid; sodium amide; In methanol; ethanol; water;
DOI:10.1248/cpb.36.373

Reference yield:

: 108781-05-1
2-Cyano-2-(3,4,5-trimethoxy-phenyl)-octanoic acid ethyl ester

: 108781-09-5
2-{3-[3-(2-Methoxy-phenoxy)-propylamino]-propyl}-2-(3,4,5-trimethoxy-phenyl)-octanenitrile

Guidance literature:: Multi-step reaction with 4 steps

1: NaOH / H₂O; methanol / 2 h / Heating

2: 1.) NaNH₂

3: aq. (COOH)2

4: 2.) NaBH₄ / 1.) EtOH, 1.5 h, reflux, 2.) EtOH, ice water, 1 h, room temp.

With sodium hydroxide; sodium tetrahydroborate; oxalic acid; sodium amide; In methanol; water;
DOI:10.1248/cpb.36.373