8-(5-(4-(benzyloxy)benzyl)-4-(4-methoxybenzyl)-1-methyl-1H-imidazol-2-yl)1,4-dioxa-8-azaspiro-[4,5]decane

Base Information

Chemical Name:8-(5-(4-(benzyloxy)benzyl)-4-(4-methoxybenzyl)-1-methyl-1H-imidazol-2-yl)1,4-dioxa-8-azaspiro-[4,5]decane
CAS No.:1161831-21-5
Molecular Formula:C₃₃H₃₇N₃O₄
Molecular Weight:539.674
Hs Code.:

Synonyms:8-(5-(4-(benzyloxy)benzyl)-4-(4-methoxybenzyl)-1-methyl-1H-imidazol-2-yl)1,4-dioxa-8-azaspiro-[4,5]decane

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Chemical Property of 8-(5-(4-(benzyloxy)benzyl)-4-(4-methoxybenzyl)-1-methyl-1H-imidazol-2-yl)1,4-dioxa-8-azaspiro-[4,5]decane

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Technology Process of 8-(5-(4-(benzyloxy)benzyl)-4-(4-methoxybenzyl)-1-methyl-1H-imidazol-2-yl)1,4-dioxa-8-azaspiro-[4,5]decane

There total 1 articles about 8-(5-(4-(benzyloxy)benzyl)-4-(4-methoxybenzyl)-1-methyl-1H-imidazol-2-yl)1,4-dioxa-8-azaspiro-[4,5]decane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 1161831-09-9
N-(1-(4-(benzyloxy)phenyl)-4-(4-methoxyphenyl)but-3-yn-2-yl)-N-methylcyanamide

: 177-11-7
4,4-ethylenedioxy-piperidine

: 1161831-21-5
8-(5-(4-(benzyloxy)benzyl)-4-(4-methoxybenzyl)-1-methyl-1H-imidazol-2-yl)1,4-dioxa-8-azaspiro-[4,5]decane

Guidance literature:: With lanthanum(lll) triflate; In isopropyl alcohol; at 95 ℃;
DOI:10.1002/anie.200900160

Reference yield: 91.0%

: 1161831-21-5
8-(5-(4-(benzyloxy)benzyl)-4-(4-methoxybenzyl)-1-methyl-1H-imidazol-2-yl)1,4-dioxa-8-azaspiro-[4,5]decane

: 1161831-26-0
1-(5-(4-(benzyloxy)benzyl)-4-(4-methoxybenzyl)-1-methyl-1H-imidazol-2-yl)piperidin-4-one

Guidance literature:: 8-(5-(4-(benzyloxy)benzyl)-4-(4-methoxybenzyl)-1-methyl-1H-imidazol-2-yl)1,4-dioxa-8-azaspiro-[4,5]decane; With hydrogenchloride; water; In acetonitrile; at 95 ℃; for 24h;

With water; sodium hydrogencarbonate; In acetonitrile; at 20 ℃; for 0.166667h;
DOI:10.1002/anie.200900160