2-amino-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile

Base Information

• Chemical Name: 2-amino-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
• CAS No.: 107752-89-6
• Molecular Formula: C₁₆H₁₄N₂O₂
• Molecular Weight: 266.299
• Mol file: 107752-89-6.mol

Synonyms:2-amino-5,6,7,8-tetrahydro-5-oxo-4-phenyl-4H-1-benzopyran-3-carbonitrile

Chemical Property of 2-amino-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

2-Amino-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-amino-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile

There total 5 articles about 2-amino-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1,3-cylohexanedione (504-02-9) + benzaldehyde (100-52-7) + malononitrile (109-77-3) → 2-amino-5,6,7,8-tetrahydro-5-oxo-4-phenyl-4H-1-benzopyran-3-carbonitrile (107752-89-6)

Guidance literature:

With poly(4-vinylpyridine) supported on MCM-48; In water; at 95 ℃; for 2h; Reflux;

DOI:10.1016/j.catcom.2011.04.004

Reference yield: 96.0%

→ 2-amino-5,6,7,8-tetrahydro-5-oxo-4-phenyl-4H-1-benzopyran-3-carbonitrile (107752-89-6)

Guidance literature:

With Candida rugosa lipase; In 1,2-dimethoxyethane; water; at 50 ℃; for 0.5h; Enzymatic reaction;

Reference yield: 92.0%

Benzylidenemalononitrile (2700-22-3) + 1,3-cylohexanedione (504-02-9) → 2-amino-5,6,7,8-tetrahydro-5-oxo-4-phenyl-4H-1-benzopyran-3-carbonitrile (107752-89-6)

Guidance literature:

With piperidine; In ethanol; for 0.05h; Ambient temperature;

upstream raw materials:

Benzylidenemalononitrile

1,3-cylohexanedione

2-phenyl-4,4,6-trimethyltetrahydro-(2H)-1,3-oxazine

1,3-Cyclohexanedione

Downstream raw materials:

10-phenyl-2,4-dithioxo-1,2,6,7,8,10-hexahydro-9-oxa-1,3-diazaanthracen-5-one

N-(3-cyano-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromen-2-yl)formamide

C₁₇H₁₆N₄O₂

C₂₃H₂₀N₄O₂