6-benzyloxy-2-[4-1[2-(1-pyrrolidinyl)ethoxy]phenyl]enzo[b]thiophen-3-yl 3-methoxy-4-[(2-oxopyrrolidin-1-yl)-methyl]phenyl ketone

Base Information

Chemical Name:6-benzyloxy-2-[4-1[2-(1-pyrrolidinyl)ethoxy]phenyl]enzo[b]thiophen-3-yl 3-methoxy-4-[(2-oxopyrrolidin-1-yl)-methyl]phenyl ketone
CAS No.:215606-47-6
Molecular Formula:C₄₀H₄₀N₂O₅S
Molecular Weight:660.834
Hs Code.:

Synonyms:6-benzyloxy-2-[4-1[2-(1-pyrrolidinyl)ethoxy]phenyl]enzo[b]thiophen-3-yl 3-methoxy-4-[(2-oxopyrrolidin-1-yl)-methyl]phenyl ketone

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Chemical Property of 6-benzyloxy-2-[4-1[2-(1-pyrrolidinyl)ethoxy]phenyl]enzo[b]thiophen-3-yl 3-methoxy-4-[(2-oxopyrrolidin-1-yl)-methyl]phenyl ketone

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Technology Process of 6-benzyloxy-2-[4-1[2-(1-pyrrolidinyl)ethoxy]phenyl]enzo[b]thiophen-3-yl 3-methoxy-4-[(2-oxopyrrolidin-1-yl)-methyl]phenyl ketone

There total 1 articles about 6-benzyloxy-2-[4-1[2-(1-pyrrolidinyl)ethoxy]phenyl]enzo[b]thiophen-3-yl 3-methoxy-4-[(2-oxopyrrolidin-1-yl)-methyl]phenyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 123-75-1
pyrrolidine

: 215606-45-4
6-Benzyloxy-2-[4-[2-(t-butyldimethylsilyloxy)ethoxy]-phenyl]benzo[b]thiophen-3-yl 3-Methoxy-4-[(2-oxopyrrolidin-1-yl)methyl]phenyl Ketone

: 215606-47-6
6-benzyloxy-2-[4-1[2-(1-pyrrolidinyl)ethoxy]phenyl]enzo[b]thiophen-3-yl 3-methoxy-4-[(2-oxopyrrolidin-1-yl)-methyl]phenyl ketone

Guidance literature:: 6-Benzyloxy-2-[4-[2-(t-butyldimethylsilyloxy)ethoxy]-phenyl]benzo[b]thiophen-3-yl 3-Methoxy-4-[(2-oxopyrrolidin-1-yl)methyl]phenyl Ketone; With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 0.75h;

pyrrolidine; With methanesulfonyl chloride; In pyridine; at 60 ℃; for 1.33333h;

Reference yield: 43.0%

: 215606-47-6
6-benzyloxy-2-[4-1[2-(1-pyrrolidinyl)ethoxy]phenyl]enzo[b]thiophen-3-yl 3-methoxy-4-[(2-oxopyrrolidin-1-yl)-methyl]phenyl ketone

: 215606-50-1
6-benzyloxy-3-[3-methoxy-4-[(2-oxopyrrolidin-1-yl)methyl]benzyl]-2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophene

Guidance literature:: 6-benzyloxy-2-[4-1[2-(1-pyrrolidinyl)ethoxy]phenyl]enzo[b]thiophen-3-yl 3-methoxy-4-[(2-oxopyrrolidin-1-yl)-methyl]phenyl ketone; With diisobutylaluminium hydride; In dichloromethane; toluene; at 0 ℃; for 0.916667h;

With triethylsilane; trifluoroacetic acid; In dichloromethane; at 0 ℃; for 1h;