beta-Carbolin-3-carboxylic acid (2-phenylethyl)amide

Base Information

Chemical Name:beta-Carbolin-3-carboxylic acid (2-phenylethyl)amide
CAS No.:78538-75-7
Molecular Formula:C₂₀H₁₇N₃O
Molecular Weight:315.374
Hs Code.:
DSSTox Substance ID:DTXSID701211693

Synonyms:GISJKULBPFTPDV-UHFFFAOYSA-N;DTXSID701211693;STL516692;AKOS030504149;78538-75-7;N-(2-phenylethyl)-9H-beta-carboline-3-carboxamide;beta-carbolin-3-carboxylic acid (2-phenylethyl)amide;N-(2-phenylethyl)-9H-pyrido[3,4-b]indole-3-carboxamide

Suppliers and Price of beta-Carbolin-3-carboxylic acid (2-phenylethyl)amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of beta-Carbolin-3-carboxylic acid (2-phenylethyl)amide

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:315.137162174
Heavy Atom Count:24
Complexity:435

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CCNC(=O)C2=NC=C3C(=C2)C4=CC=CC=C4N3

Technology Process of beta-Carbolin-3-carboxylic acid (2-phenylethyl)amide

There total 6 articles about beta-Carbolin-3-carboxylic acid (2-phenylethyl)amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 69954-48-9
methyl 9H-β-carboline-3-carboxylate

: 64-04-0
phenethylamine

: 78538-75-7
N-(2-phenylethyl)-9H-β-carboline-3-carboxamide

Guidance literature:: With lanthanum(lll) triflate; In 1,4-dioxane; at 120 ℃; for 20h; Inert atmosphere; Glovebox;
DOI:10.1021/jacs.6b12569

Reference yield:

: 21109-25-1
1-(1H-indol-2-yl)methanamine

: 59795-89-0
phenethyl isocyanide

: 78538-75-7
N-(2-phenylethyl)-9H-β-carboline-3-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 15 h / 20 °C

2: hydrogenchloride / water; 1,4-dioxane / 48 h / 20 °C

With hydrogenchloride; In 1,4-dioxane; methanol; water; 1: |Ugi Condensation;
DOI:10.1021/acs.orglett.9b00778