DL-3-Amino-3-(2-naphthyl)propionic acid

Base Information

• Chemical Name: DL-3-Amino-3-(2-naphthyl)propionic acid
• CAS No.: 129042-57-5
• Molecular Formula: C13H13 N O2
• Molecular Weight: 215.252
• Hs Code.: 2922499990
• DSSTox Substance ID: DTXSID10441748
• Nikkaji Number: J3.590.242B
• ChEMBL ID: CHEMBL4165875
• Mol file: 129042-57-5.mol

Synonyms:129042-57-5;DL-3-Amino-3-(2-naphthyl)propionic acid;DL-3-Amino-3-(2-naphthyl)-propionic acid;3-AMINO-3-(NAPHTHALEN-2-YL)PROPANOIC ACID;3-amino-3-naphthalen-2-ylpropanoic acid;3-Amino-3-naphthalen-2-yl-propionic acid;3-AMINO-3-(2-NAPHTHYL)PROPIONIC ACID;3-AMINO-3-(2-NAPHTHYL)PROPANOIC ACID;MFCD01871322;3-(2-NAPHTHYL)-BETA-ALANINE;SCHEMBL5720949;CHEMBL4165875;DTXSID10441748;FD1088;AKOS000177444;AKOS016842460;AB10472;AB17730;AB17798;2-Naphthalenepropanoic acid, beta-amino-;AC-23769;DS-13402;SY033887;(R)-3-Amino-3-(2-naphthyl)-propionicacid;CS-0155884;FT-0687320;beta-(beta-naphthyl)-beta-aminopropionic acid;J3.590.242B;EN300-137597;A805893;Z317027278;3-amino-3-(2-naphthyl)propanoic acid;3-Amino-3-(2-naphthyl)propionic Acid;(R)-3-Amino-3-(naphthalen-2-yl)propanoic acid;(R)-3-Amino-3-(2-naphthyl)-propionic acid

Chemical Property of DL-3-Amino-3-(2-naphthyl)propionic acid

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 412.337°C at 760 mmHg
• Flash Point: 203.175°C
• PSA: 63.32000
• Density: 1.252g/cm³
• LogP: 3.01460
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: -0.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 215.094628657
• Heavy Atom Count: 16
• Complexity: 254

Purity/Quality:

99% ^*data from raw suppliers

Dl-3-Amino-3-(2-Naphthyl)PropionicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C=C(C=CC2=C1)C(CC(=O)O)N

Technology Process of DL-3-Amino-3-(2-naphthyl)propionic acid

There total 4 articles about DL-3-Amino-3-(2-naphthyl)propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

malonic acid (141-82-2) + β-naphthaldehyde (66-99-9) → 3-amino-3-(2-naphthyl)propionic acid (129042-57-5,767282-94-0,786637-72-7)

Guidance literature:

With ammonium acetate; In butan-1-ol; Reflux;

DOI:10.1016/j.ejmech.2018.07.005

Reference yield:

3-(2-naphthyl)acrylic acid (51557-26-7) → 3-amino-3-(2-naphthyl)propionic acid (129042-57-5,767282-94-0,786637-72-7)

Guidance literature:

With ethanol; hydroxylamine;

Reference yield:

→ 3-amino-3-(2-naphthyl)propionic acid (129042-57-5,767282-94-0,786637-72-7)

Guidance literature:

upstream raw materials:

3-(2-naphthyl)acrylic acid

malonic acid

β-naphthaldehyde

Downstream raw materials:

3-(1,3-dioxoisoindolin-2-yl)-3-(naphthalen-2-yl)propanoic acid

(R)-3-amino-3-(2-naphthyl)propanoic acid

C₁₈H₂₁NO₄

(R,S)-ethyl 3-{3-[6-(3-benzylureido)indolin-1-yl]-3-oxopropanoylamino}-3-(naphthalen-2-yl)propanoate