(E)-3-(naphthalen-2-yl)acrylic acid

Base Information

• Chemical Name: (E)-3-(naphthalen-2-yl)acrylic acid
• CAS No.: 51557-26-7
• Molecular Formula: C13H10O2
• Molecular Weight: 198.221
• Hs Code.: 2916399090
• European Community (EC) Number: 672-249-9
• Nikkaji Number: J852.898E,J2.186.027A
• ChEMBL ID: CHEMBL1891545
• Mol file: 51557-26-7.mol

Synonyms:3-(2-Naphthyl)Acrylic Acid;2-Naphthylacrylic acid;51557-26-7;(E)-3-(naphthalen-2-yl)acrylic acid;49711-14-0;3-(Naphthalen-2-yl)acrylic acid;3-naphthalen-2-yl-acrylic acid;(E)-3-naphthalen-2-ylprop-2-enoic acid;3-(naphth-2-yl)acrylic acid;(2E)-3-(naphthalen-2-yl)prop-2-enoic acid;3-(naphthalen-2-yl)prop-2-enoic acid;(E)-3-naphthalen-2-yl-acrylic acid;SCHEMBL78426;AB-131/40897182;CHEMBL1891545;Propenoic acid,3-(2-naphtyl)-;MFCD00209666;(E)-3-(naphthalen-2-yl)acrylicacid;2-Propenoic acid, 3-(2-naphtyl)-;AKOS000140514;trans-3-(naphth-2-yl)-propenoic acid;(E)-3-(2-naphthyl)prop-2-enoic acid;2-Propenoic acid, 3-(2-naphthalenyl)-;NCGC00186311-01;NCGC00186311-02;NCGC00186311-03;AC-18959;MS-11477;(E)-3-(napthalen-2-yl)-2-propenoic acid;(2E)-3-(2-Naphthyl)-2-propenoic acid #;CS-0356747;EN300-138574;EN300-833099;F3395-0158;Z2942853570

Chemical Property of (E)-3-(naphthalen-2-yl)acrylic acid

Chemical Property:

• Appearance/Colour: Powder
• Vapor Pressure: 2.15E-05mmHg at 25°C
• Melting Point: 210-212ºC
• Refractive Index: 1.665
• Boiling Point: 393.1ºC at 760 mmHg
• PKA: 4.46±0.30(Predicted)
• Flash Point: 290.7ºC
• PSA: 37.30000
• Density: 1.245 g/cm³
• LogP: 2.93760
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 198.068079557
• Heavy Atom Count: 15
• Complexity: 257

Purity/Quality:

99% ^*data from raw suppliers

2-NaphthylacrylicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39-37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C=C(C=CC2=C1)C=CC(=O)O
• Isomeric SMILES: C1=CC=C2C=C(C=CC2=C1)/C=C/C(=O)O

Technology Process of (E)-3-(naphthalen-2-yl)acrylic acid

There total 1 articles about (E)-3-(naphthalen-2-yl)acrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-naphthalenylmagnesium bromide (21473-01-8) → 3-(2-naphthyl)acrylic acid (51557-26-7)

Guidance literature:

Multi-step reaction with 2 steps

1: Zersetzung des Reaktionsproduktes mit verd. Salzsaeure

2: aniline

With aniline;

Reference yield: 90.0%

3-(2-naphthyl)acrylic acid (51557-26-7) + Diphenylphosphine oxide (4559-70-0) → (E)-(2-(naphthalen-2-yl)vinyl)diphenylphosphine oxide (1310329-69-1)

Guidance literature:

With copper(I) oxide; 1,10-Phenanthroline; silver(l) oxide; In 1-methyl-pyrrolidin-2-one; at 120 ℃; for 6h; regioselective reaction; Inert atmosphere;

DOI:10.1002/chem.201003561

Reference yield: 88.0%

3-(2-naphthyl)acrylic acid (51557-26-7) + diphenylamine (122-39-4) → 4-(naphthalen-2-yl)-1-phenylquinolin-2(1H)-one

Guidance literature:

With 1,10-Phenanthroline; palladium(II) trimethylacetate; copper diacetate; trifluoroacetic acid; In methanol; at 110 ℃; for 24h;

DOI:10.1002/chem.201500774

upstream raw materials:

2-naphthalenylmagnesium bromide

Downstream raw materials:

3-amino-3-(2-naphthyl)propionic acid

3-chloronaphtho<1,2-b>thiophene-2-carbonyl chloride

(E)-(2-(naphthalen-2-yl)vinyl)diphenylphosphine oxide

(E)-N-benzyl-N-methyl-3-(naphthalene-2-yl)-acrylamide