Cbz-N-methyl-L-valine

Base Information

Chemical Name:Cbz-N-methyl-L-valine
CAS No.:42417-65-2
Molecular Formula:C14H19NO4
Molecular Weight:265.309
Hs Code.:2922509090
European Community (EC) Number:610-027-5
DSSTox Substance ID:DTXSID00426827
Nikkaji Number:J494.842D
Wikidata:Q72516320
Mol file:42417-65-2.mol

Synonyms:(S)-N-(Benzyloxycarbonyl)-N-methylvaline;N-(Benzyloxycarbonyl)-N-methylvaline;Cbz-N-Me-Val-OH;

Suppliers and Price of Cbz-N-methyl-L-valine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Z-N-methyl-L-valine
1g
$ 360.00

TRC
(S)-N-(Benzyloxycarbonyl)-N-methylvaline
5g
$ 225.00

Iris Biotech GmbH
Z-L-MeVal-OH
5 g
$ 337.50

Iris Biotech GmbH
Z-L-MeVal-OH
1 g
$ 87.75

Crysdot
(S)-2-(((Benzyloxy)carbonyl)(methyl)amino)-3-methylbutanoicacid 97%
10g
$ 115.00

Crysdot
(S)-2-(((Benzyloxy)carbonyl)(methyl)amino)-3-methylbutanoicacid 97%
25g
$ 230.00

chempep
Z-N-Me-Val-OH
25g
$ 800.00

chempep
Z-N-Me-Val-OH
5g
$ 220.00

Chem-Impex
Z--methyl-L-valine ≥ 98% (HPLC)
1G
$ 41.40

Chem-Impex
Z-N-methyl-L-valine,98%(HPLC) 98%(HPLC)
5G
$ 197.12

Total 57 raw suppliers

Chemical Property of Cbz-N-methyl-L-valine

Chemical Property:

Vapor Pressure:2.34E-07mmHg at 25°C
Melting Point:68-70 °C(lit.)
Refractive Index:1.532
Boiling Point:407.1 °C at 760 mmHg
PKA:4.01±0.10(Predicted)
Flash Point:200 °C
PSA：66.84000
Density:1.167 g/cm³
LogP:2.36420
Storage Temp.:Store at RT.
Solubility.:Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:265.13140809
Heavy Atom Count:19
Complexity:311

Purity/Quality:

98% ^*data from raw suppliers

Z-N-methyl-L-valine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 36/37

MSDS Files:

Useful:

Canonical SMILES:CC(C)C(C(=O)O)N(C)C(=O)OCC1=CC=CC=C1
Isomeric SMILES:CC(C)[C@@H](C(=O)O)N(C)C(=O)OCC1=CC=CC=C1
Uses (S)-N-(Benzyloxycarbonyl)-N-methylvaline has been used as a reactant in the synthesis of a biologically active cyclodepsipeptide destruxin E which is a potent negative regulator of osteoclast morphology.

Technology Process of Cbz-N-methyl-L-valine

There total 10 articles about Cbz-N-methyl-L-valine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 66866-64-6
(4S)-4-isopropyl-5-oxo-1,3-oxazolidine-3-carboxylic acid benzyl ester

: 42417-65-2
Z-MeVal-OH

Guidance literature:: With chloro-trimethyl-silane; sodium cyanoborohydride; In acetonitrile; for 0.166667h; Ambient temperature;
DOI:10.1246/cl.1999.299

Reference yield: 78.0%

: 1149-26-4
(S)-N-(benzyloxycarbonyl)valine

: 74-88-4
methyl iodide

: 42417-65-2
Z-MeVal-OH

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 20 ℃; for 24h;
DOI:10.7164/antibiotics.55.322

Reference yield:

: 1149-26-4
(S)-N-(benzyloxycarbonyl)valine

: 42417-65-2
Z-MeVal-OH

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / CSA / toluene / Heating

2: Et₃SiH; CF₃COOH / CH₂Cl₂

With triethylsilane; trifluoroacetic acid; camphor-10-sulfonic acid; In dichloromethane; toluene;
DOI:10.1002/hlca.200690235