N-Fmoc-N-methyl-O-benzyl-L-serine

Base Information

Chemical Name:N-Fmoc-N-methyl-O-benzyl-L-serine
CAS No.:84000-14-6
Molecular Formula:C26H25 N O5
Molecular Weight:431.488
Hs Code.:
Mol file:84000-14-6.mol

Synonyms:Fmoc-N-Me-Ser(Bzl)-OH; N-(9-Fluorenylmethyloxycarbonyl)-N-methyl-O-benzyl-L-serine

Suppliers and Price of N-Fmoc-N-methyl-O-benzyl-L-serine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Fmoc-N-methyl-O-benzyl-L-serine
1g
$ 363.00

Usbiological
Fmoc-N-methyl-O-benzyl-L-serine 99+%
1g
$ 199.00

TRC
Fmoc-N-Me-Ser(Bzl)-OH
500mg
$ 65.00

TRC
Fmoc-N-Me-Ser(Bzl)-OH
250mg
$ 55.00

TRC
Fmoc-N-Me-Ser(Bzl)-OH
100mg
$ 45.00

Matrix Scientific
Fmoc-Nalpha-methyl-O-benzyl-L-serine
5g
$ 844.00

Matrix Scientific
Fmoc-Nalpha-methyl-O-benzyl-L-serine
1g
$ 236.00

Iris Biotech GmbH
Fmoc-L-MeSer(Bzl)-OH
5 g
$ 337.50

Iris Biotech GmbH
Fmoc-L-MeSer(Bzl)-OH
1 g
$ 101.25

Crysdot
Fmoc-MeSer(Bzl)-OH 95+%
1g
$ 75.00

Total 26 raw suppliers

Chemical Property of N-Fmoc-N-methyl-O-benzyl-L-serine

Chemical Property:

Boiling Point:618.9±55.0 °C(Predicted)
PKA:3.43±0.10(Predicted)
PSA：76.07000
Density:1.264±0.06 g/cm3(Predicted)
LogP:4.53730
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

Fmoc-N-methyl-O-benzyl-L-serine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-Fmoc-N-methyl-O-benzyl-L-serine

There total 3 articles about N-Fmoc-N-methyl-O-benzyl-L-serine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 84000-04-4
(4S)-4-<(benzyloxy)methyl>-3-(9-fluorenylmethyloxycarbonyl)-5-oxooxazolidine

: 84000-14-6,84000-15-7
N-Fmoc-N-methyl-O-benzyl-L-serine

Guidance literature:: With triethylsilane; trifluoroacetic acid; In chloroform; for 22h; Ambient temperature;
DOI:10.1021/jo00149a016

Reference yield:

: 122889-11-6,83792-48-7
O-benzyl-N-Fmoc-L-serine

: 84000-14-6,84000-15-7
N-Fmoc-N-methyl-O-benzyl-L-serine

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / p-toluenesulfonic acid / toluene / 1 h / Heating

2: 96 percent / triflouroacetic acid, triethylsilane / CHCl₃ / 22 h / Ambient temperature

With triethylsilane; toluene-4-sulfonic acid; trifluoroacetic acid; In chloroform; toluene;
DOI:10.1021/jo00149a016

Reference yield:

: 122889-11-6,83792-48-7
O-benzyl-N-Fmoc-L-serine

: 84000-14-6
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-O-(phenylmethyl)-L-serine

Guidance literature:: Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / toluene / 2 h / Reflux

2: triethylsilane; trifluoroacetic acid / acetonitrile / 2 h / 75 °C / Flow reactor

With triethylsilane; toluene-4-sulfonic acid; trifluoroacetic acid; In toluene; acetonitrile;
DOI:10.1002/ejoc.201300705