tert-butyl O-benzyl-N-methyl-L-serine

Base Information

• Chemical Name: tert-butyl O-benzyl-N-methyl-L-serine
• CAS No.: 960243-40-7
• Molecular Formula: C₁₅H₂₃NO₃
• Molecular Weight: 265.353
• Mol file: 960243-40-7.mol

Synonyms:tert-butyl O-benzyl-N-methyl-L-serine

Chemical Property of tert-butyl O-benzyl-N-methyl-L-serine

Chemical Property:

Purity/Quality:

99.00% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl O-benzyl-N-methyl-L-serine

There total 2 articles about tert-butyl O-benzyl-N-methyl-L-serine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C30H33NO5 → tert-butyl O-benzyl-N-methyl-L-serine (960243-40-7)

Guidance literature:

With piperidine; at 20 ℃;

DOI:10.1016/j.tetlet.2007.09.098

Reference yield:

tert-Butyl 2,2,2-trichloroacetimidate (98946-18-0) + N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-O-(phenylmethyl)-L-serine (84000-14-6) → tert-butyl O-benzyl-N-methyl-L-serine (960243-40-7)

Guidance literature:

tert-Butyl 2,2,2-trichloroacetimidate; N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-O-(phenylmethyl)-L-serine; Inert atmosphere;

With piperidine; In N,N-dimethyl-formamide; Inert atmosphere;

DOI:10.1016/j.tetasy.2009.09.022

Reference yield: 65.0%

tert-butyl O-benzyl-N-methyl-L-serine (960243-40-7) + (2R,3R)-3-azido-4-(tert-butyldiphenylsilyloxy)-1,2-epoxybutane (201933-46-2) → C35H48N4O5Si (960243-43-0)

Guidance literature:

(2R,3R)-3-azido-4-(tert-butyldiphenylsilyloxy)-1,2-epoxybutane; With ytterbium(III) triflate; In dichloromethane; at 20 ℃; for 0.333333h; Inert atmosphere;

tert-butyl O-benzyl-N-methyl-L-serine; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.tetasy.2009.09.022

upstream raw materials:

tert-Butyl 2,2,2-trichloroacetimidate

N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-O-(phenylmethyl)-L-serine

Downstream raw materials:

C₃₅H₄₈N₄O₅Si