methyl 4-[(5-chloro-6-isobutoxypyridin-3-yl)oxy]-2,5-difluorobenzoate

Base Information

Chemical Name:methyl 4-[(5-chloro-6-isobutoxypyridin-3-yl)oxy]-2,5-difluorobenzoate
CAS No.:1446444-55-8
Molecular Formula:C₁₇H₁₆ClF₂NO₄
Molecular Weight:371.768
Hs Code.:

Synonyms:methyl 4-[(5-chloro-6-isobutoxypyridin-3-yl)oxy]-2,5-difluorobenzoate

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Chemical Property of methyl 4-[(5-chloro-6-isobutoxypyridin-3-yl)oxy]-2,5-difluorobenzoate

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Technology Process of methyl 4-[(5-chloro-6-isobutoxypyridin-3-yl)oxy]-2,5-difluorobenzoate

There total 2 articles about methyl 4-[(5-chloro-6-isobutoxypyridin-3-yl)oxy]-2,5-difluorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1355066-42-0
5-chloro-6-isobutoxypyridin-3-ol

: 20372-66-1
methyl 2,4,5-trifluorobenzoate

: 1446444-55-8
methyl 4-[(5-chloro-6-isobutoxypyridin-3-yl)oxy]-2,5-difluorobenzoate

Guidance literature:: With potassium carbonate; In dimethyl sulfoxide; at 50 ℃; for 16h;

Reference yield:

: 1217500-89-4
5-chloro-6-isobutoxypyridin-3-ylboronic acid

: 1446444-55-8
methyl 4-[(5-chloro-6-isobutoxypyridin-3-yl)oxy]-2,5-difluorobenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: peracetic acid; acetic acid / water / 3.17 h / 0 - 20 °C

2: potassium carbonate / dimethyl sulfoxide / 16 h / 50 °C

With peracetic acid; potassium carbonate; acetic acid; In water; dimethyl sulfoxide;