20372-66-1

Usage

Uses

Methyl 2,4,5-trifluorobenzoate

InChI:InChI=1/C8H5F3O2/c1-13-8(12)4-2-6(10)7(11)3-5(4)9/h2-3H,1H3

Upstream product

• 446-17-3 2,4,5-trifluorobenzoic acid 
• 67-56-1 methanol 
• 88419-56-1 2,4,5-trifluorobenzoyl chloride 

Downstream Products

• 181824-36-2 4-Dimethylamino-2,5-difluoro-benzoic acid methyl ester 
• 181821-02-3 2-(4-Dimethylamino-2,5-difluoro-phenylmethanesulfinyl)-N-pyridin-4-yl-nicotinamide 
• 181819-74-9 (4-Dimethylamino-2,5-difluoro-phenyl)-methanol 
• 918967-69-8 2,5-difluoro-4-methylsulfanyl-benzoic acid methyl ester 
• 200007-66-5 methyl 4-cyano-2,5-difluorobenzoate 
• 1446444-60-5 methyl 2,5-difluoro-4-(2-methoxyphenoxy)benzoate 
• 1446444-63-8 tert-butyl 4-[(5-chloro-6-fluoropyridin-3-yl)oxy]-2,5-difluorobenzoate 
• 1446444-61-6 methyl 2,5-difluoro-4-(3-methoxyphenoxy)benzoate 
• 1354963-13-5 methyl 4-(4-chloro-2-methoxyphenoxy)-2,5-difluorobenzoate 
• 1446444-62-7 4-((5-chloro-6-fluoropyridin-3-yl)oxy)-2,5-difluorobenzoic acid 
• 1446444-45-6 4-((5-chloro-6-((1,1,1,3,3,3-hexafluoropropan-2-yl)oxy)pyridin-3-yl)oxy)-N-[(dimethylamino)sulfonyl]-2,5-difluorobenzamide 
• 1446444-44-5 4-((5-chloro-6-((1,1,1-trifluoropropan-2-yl)oxy)pyridin-3-yl)oxy)-N-[(dimethylamino)sulfonyl]-2,5-difluorobenzamide 
• 1446444-16-1 4-{[5-chloro-6-(3-fluoropyrrolidin-1-yl)pyridine-3-yl]oxy}-N-[(dimethylamino)sulfonyl]-2,5-difluorobenzamide formate salt 
• 1446444-50-3 4-[(5-chloro-6-fluoropyridin-3-yl)oxy]-2,5-difluoro-N-[(dimethylamino)sulfonyl]benzamide 

Relevant academic research and scientific papers

GPCR AGONISTS

Compounds of formula (I): or pharmaceutically acceptable salts thereof, are GPCR agonists and are useful as for the treatment of obesity and diabetes.

A convenient synthesis of n-substituted 2,3-dihydro-3-oxoisothiazolo[5,4-b]pyridines in acidic conditions

A novel and convenient synthesis of N-substituted 2,3-dihydro-3-oxoisothiazolo[5,4-b]pyridines which possess potent in vitro inhibitory activity against gastric (H+/K+)-ATPase is reported. Compared with the methods reported previously, the compounds were synthesized more readily in relatively high yields by conversion of N-substituted 2-(benzyl-, 1-phenylethyl-, and benzhydrylsulfinyl)nicotinamides (17d-l) in a diluted hydrochloric acid-methanol solution at room temperature.