Benzyloxy-acetic acid (R)-2-benzyloxy-2-[(2R,3S)-3-benzyloxy-4-oxo-1-((R)-1-phenyl-ethyl)-azetidin-2-yl]-ethyl ester

Base Information

Chemical Name:Benzyloxy-acetic acid (R)-2-benzyloxy-2-[(2R,3S)-3-benzyloxy-4-oxo-1-((R)-1-phenyl-ethyl)-azetidin-2-yl]-ethyl ester
CAS No.:188983-45-1
Molecular Formula:C₃₆H₃₇NO₆
Molecular Weight:579.693
Hs Code.:

Synonyms:Benzyloxy-acetic acid (R)-2-benzyloxy-2-[(2R,3S)-3-benzyloxy-4-oxo-1-((R)-1-phenyl-ethyl)-azetidin-2-yl]-ethyl ester

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Chemical Property of Benzyloxy-acetic acid (R)-2-benzyloxy-2-[(2R,3S)-3-benzyloxy-4-oxo-1-((R)-1-phenyl-ethyl)-azetidin-2-yl]-ethyl ester

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Technology Process of Benzyloxy-acetic acid (R)-2-benzyloxy-2-[(2R,3S)-3-benzyloxy-4-oxo-1-((R)-1-phenyl-ethyl)-azetidin-2-yl]-ethyl ester

There total 1 articles about Benzyloxy-acetic acid (R)-2-benzyloxy-2-[(2R,3S)-3-benzyloxy-4-oxo-1-((R)-1-phenyl-ethyl)-azetidin-2-yl]-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 19810-31-2
Benzyloxyacetyl chloride

: 188983-39-3
(R)-2-Benzyloxy-3-[(E)-(R)-1-phenyl-ethylimino]-propan-1-ol

: 2-Benzyloxy-N-((R)-1-phenyl-ethyl)-acetamide

: 188983-45-1
Benzyloxy-acetic acid (R)-2-benzyloxy-2-[(2R,3S)-3-benzyloxy-4-oxo-1-((R)-1-phenyl-ethyl)-azetidin-2-yl]-ethyl ester

: Benzyloxy-acetic acid (R)-2-benzyloxy-2-[(2S,3R)-3-benzyloxy-4-oxo-1-((R)-1-phenyl-ethyl)-azetidin-2-yl]-ethyl ester

Guidance literature:: With triethylamine; In dichloromethane; at -20 - 25 ℃;

Reference yield: 90.0%

: 188983-45-1
Benzyloxy-acetic acid (R)-2-benzyloxy-2-[(2R,3S)-3-benzyloxy-4-oxo-1-((R)-1-phenyl-ethyl)-azetidin-2-yl]-ethyl ester

: 188983-51-9
(3S,4R)-3-Benzyloxy-4-((R)-1-benzyloxy-2-hydroxy-ethyl)-1-((R)-1-phenyl-ethyl)-azetidin-2-one

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; methanol; at 0 ℃; for 0.5h;

Reference yield:

: 188983-45-1
Benzyloxy-acetic acid (R)-2-benzyloxy-2-[(2R,3S)-3-benzyloxy-4-oxo-1-((R)-1-phenyl-ethyl)-azetidin-2-yl]-ethyl ester

: 188983-56-4
(R)-2-Benzyloxy-2-[(2S,3R)-3-benzyloxy-1-((R)-1-phenyl-ethyl)-azetidin-2-yl]-ethanol

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / NaOH / tetrahydrofuran; methanol / 0.5 h / 0 °C

2: 67 percent / LiAlH₄/AlCl₃ / diethyl ether / 2 h / Heating

With sodium hydroxide; lithium aluminium tetrahydride; aluminium trichloride; In tetrahydrofuran; methanol; diethyl ether;