2-Bromopyridine-5-boronic acid

Base Information

Chemical Name:2-Bromopyridine-5-boronic acid
CAS No.:223463-14-7
Molecular Formula:C5H5BBrNO2
Molecular Weight:201.815
Hs Code.:29333990
European Community (EC) Number:672-028-7
DSSTox Substance ID:DTXSID70376380
Nikkaji Number:J1.720.049F
Wikidata:Q72511837
ChEMBL ID:CHEMBL3236616
Mol file:223463-14-7.mol

Synonyms:2-bromopyridine-5-boronic acid

Suppliers and Price of 2-Bromopyridine-5-boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Bromopyridine-5-boronic acid
5g
$ 408.00

TRC
2-Bromopyridine-5-boronicacid
500mg
$ 65.00

TCI Chemical
2-Bromopyridine-5-boronic Acid (contains varying amounts of Anhydride)
1g
$ 83.00

TCI Chemical
2-Bromopyridine-5-boronic Acid (contains varying amounts of Anhydride)
5g
$ 258.00

Synthonix
2-Bromopyridine-5-boronicacid 96%
25g
$ 120.00

Synthonix
2-Bromopyridine-5-boronicacid 96%
10g
$ 60.00

Synthonix
2-Bromopyridine-5-boronicacid 96%
5g
$ 30.00

Synthonix
2-Bromopyridine-5-boronicacid 96%
1g
$ 10.00

SynQuest Laboratories
6-Bromopyridine-3-boronic acid 97%
1 g
$ 16.00

SynQuest Laboratories
6-Bromopyridine-3-boronic acid 97%
5 g
$ 36.00

Total 116 raw suppliers

Chemical Property of 2-Bromopyridine-5-boronic acid

Chemical Property:

Vapor Pressure:9.42E-06mmHg at 25°C
Melting Point:161-166 °C
Refractive Index:1.602
Boiling Point:358.2 °C at 760 mmHg
PKA:6.62±0.10(Predicted)
Flash Point:170.4 °C
PSA：53.35000
Density:1.78 g/cm³
LogP:-0.47610
Storage Temp.:Keep Cold
Solubility.:soluble in Methanol
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:200.95967
Heavy Atom Count:10
Complexity:114

Purity/Quality:

99% ^*data from raw suppliers

2-Bromopyridine-5-boronic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38-20/21/22
Safety Statements: 26-36-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=CN=C(C=C1)Br)(O)O
Uses Reactant involved in:Iterative cross-coupling reactions for synthesis of non-cytotoxic terpyridinesThe Garlanding approach for synthesis of phenyl-pyridyl scaffoldsCyanation for synthesis of aromatic nitrilesSuzuki-Miyaura cross-coupling with dihalopyridines and dihalobipyridinesPetasis boronic Mannich reaction

Technology Process of 2-Bromopyridine-5-boronic acid

There total 5 articles about 2-Bromopyridine-5-boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 624-28-2
2,5-dibromopyridine

: 223463-14-7
6-bromopyridin-3-ylboronic acid

Guidance literature:: 2,5-dibromopyridine; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 1h; Inert atmosphere;

With Triisopropyl borate; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;

With water; sodium hydroxide; In tetrahydrofuran;
DOI:10.1016/j.tet.2009.04.049

Reference yield: 72.0%

: 624-28-2
2,5-dibromopyridine

: 5419-55-6
Triisopropyl borate

: 223463-14-7
6-bromopyridin-3-ylboronic acid

Guidance literature:: 2,5-dibromopyridine; With n-butyllithium; In tetrahydrofuran; diethyl ether; hexane; at -78 ℃; for 2h;

Triisopropyl borate; In tetrahydrofuran; diethyl ether; hexane; at -78 ℃; for 2h;