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(R)-2-(((Benzyloxy)carbonyl)amino)-4-phenylbutanoic acid

Base Information
  • Chemical Name:(R)-2-(((Benzyloxy)carbonyl)amino)-4-phenylbutanoic acid
  • CAS No.:138812-70-1
  • Molecular Formula:C18H19NO4
  • Molecular Weight:313.353
  • Hs Code.:2924299090
  • DSSTox Substance ID:DTXSID40426927
  • Wikidata:Q72502127
  • Mol file:138812-70-1.mol
(R)-2-(((Benzyloxy)carbonyl)amino)-4-phenylbutanoic acid

Synonyms:138812-70-1;(R)-2-(((Benzyloxy)carbonyl)amino)-4-phenylbutanoic acid;Z-D-HOMOPHE-OH;Cbz-D-homoPhenylalanine;Cbz-D-homophenyl-Ala;(2R)-4-phenyl-2-(phenylmethoxycarbonylamino)butanoic acid;Z-D-homophenylalanine;Cbz-D-Homophe;SCHEMBL1796250;BDBM36224;DTXSID40426927;(2R)-2-{[(benzyloxy)carbonyl]amino}-4-phenylbutanoic acid;MFCD00066107;AKOS015911471;AM83540;BS-21377;CS-0445791;EN300-6747824;(R)-2-(benzyloxycarbonylamino)-4-phenylbutanoic acid

Suppliers and Price of (R)-2-(((Benzyloxy)carbonyl)amino)-4-phenylbutanoic acid
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • Z-D-homophenylalanine
  • 1g
  • $ 353.00
  • TRC
  • Z-D-Homophe-oh
  • 250mg
  • $ 75.00
  • Crysdot
  • (R)-2-(((Benzyloxy)carbonyl)amino)-4-phenylbutanoicacid 95+%
  • 5g
  • $ 158.00
  • Crysdot
  • (R)-2-(((Benzyloxy)carbonyl)amino)-4-phenylbutanoicacid 95+%
  • 1g
  • $ 40.00
  • Crysdot
  • (R)-2-(((Benzyloxy)carbonyl)amino)-4-phenylbutanoicacid 95+%
  • 10g
  • $ 277.00
  • Crysdot
  • (R)-2-(((Benzyloxy)carbonyl)amino)-4-phenylbutanoicacid 95+%
  • 25g
  • $ 554.00
  • Chem-Impex
  • Z-D-homophenylalanine ≥ 99% (HPLC)
  • 25G
  • $ 662.00
  • Chem-Impex
  • Z-D-homophenylalanine ≥ 99% (HPLC)
  • 5G
  • $ 166.00
  • Chem-Impex
  • Z-D-homophenylalanine ≥ 99% (HPLC)
  • 1G
  • $ 41.40
  • American Custom Chemicals Corporation
  • 2-([(BENZYLOXY)CARBONYL]AMINO)-4-PHENYLBUTANOIC ACID 99.00%
  • 1G
  • $ 156.45
Total 33 raw suppliers
Chemical Property of (R)-2-(((Benzyloxy)carbonyl)amino)-4-phenylbutanoic acid
Chemical Property:
  • Melting Point:103 - 104 °C 
  • PSA:75.63000 
  • LogP:3.38970 
  • Storage Temp.:Store at RT. 
  • XLogP3:3.4
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:8
  • Exact Mass:313.13140809
  • Heavy Atom Count:23
  • Complexity:373
Purity/Quality:

95% *data from raw suppliers

Z-D-homophenylalanine *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1=CC=C(C=C1)CCC(C(=O)O)NC(=O)OCC2=CC=CC=C2
  • Isomeric SMILES:C1=CC=C(C=C1)CC[C@H](C(=O)O)NC(=O)OCC2=CC=CC=C2
  • Uses Z-D-Homophe-oh is a useful intermediate used in the synthesis of rapamycin-peptide hybrid molecules that functions as macrocyclic immunosuppressants.
Technology Process of (R)-2-(((Benzyloxy)carbonyl)amino)-4-phenylbutanoic acid

There total 13 articles about (R)-2-(((Benzyloxy)carbonyl)amino)-4-phenylbutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With lithium hydroxide; In methanol; water; at 0 - 20 ℃; for 8h;
DOI:10.1016/j.bmc.2015.09.029
Guidance literature:
With triethylamine; In tetrahydrofuran; water; at 20 ℃;
Guidance literature:
With jones reagent; In acetone; at 0 - 20 ℃; for 4h;
DOI:10.1021/jo010865a
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