C₄₀H₄₈O₁₄

Base Information

• Chemical Name: C₄₀H₄₈O₁₄
• CAS No.: 1384545-92-9
• Molecular Formula: C₄₀H₄₈O₁₄
• Molecular Weight: 752.813
• Mol file: 1384545-92-9.mol

Synonyms:C₄₀H₄₈O₁₄

Chemical Property of C₄₀H₄₈O₁₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₀H₄₈O₁₄

There total 6 articles about C₄₀H₄₈O₁₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

(E)-3-methoxy-4-allyloxycinnamoyl chloride (850786-96-8) + methyl (1S,3R,4R,5S,2'S,3'S)-1,3-dihydroxy-4,5-[2,3-dimethoxybutane-2,3-di(yloxy)]cyclohexane-1-carboxylate (183625-03-8) → C40H48O14 (1384545-92-9)

Guidance literature:

With dmap; triethylamine; In dichloromethane; for 36h; Reflux;

DOI:10.1039/c2ob25124h

Reference yield:

D-(-)-quinic acid (77-95-2) → C40H48O14 (1384545-92-9)

Guidance literature:

Multi-step reaction with 4 steps

1: (1S)-10-camphorsulfonic acid / 24 h / Reflux

2: pyridinium chlorochromate / dichloromethane / 16 h / 20 °C

3: sodium tris(acetoxy)borohydride; acetic acid / acetonitrile / 15 h / 20 °C

4: dmap; triethylamine / dichloromethane / 36 h / Reflux

With dmap; (1S)-10-camphorsulfonic acid; sodium tris(acetoxy)borohydride; acetic acid; triethylamine; pyridinium chlorochromate; In dichloromethane; acetonitrile;

DOI:10.1039/c2ob25124h

Reference yield:

(E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid (1135-24-6,537-98-4) → C40H48O14 (1384545-92-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium carbonate / acetone / 0.5 h / 20 °C

1.2: 48 h / Reflux

1.3: 2 h / Reflux

2.1: oxalyl dichloride; N,N-dimethyl-formamide / toluene / 10 h / 0 - 20 °C

3.1: dmap; triethylamine / dichloromethane / 36 h / Reflux

With dmap; oxalyl dichloride; potassium carbonate; triethylamine; N,N-dimethyl-formamide; In dichloromethane; acetone; toluene; 1.2: Williamson ether synthesis;

DOI:10.1039/c2ob25124h

upstream raw materials:

(E)-3-methoxy-4-allyloxycinnamoyl chloride

methyl (1S,3R,4R,5S,2'S,3'S)-1,3-dihydroxy-4,5-[2,3-dimethoxybutane-2,3-di(yloxy)]cyclohexane-1-carboxylate

(E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid

D-(-)-quinic acid

Downstream raw materials:

methyl 1,3-di-O-feruloyl-muco-quinate