4-(3'-(3'',5''-dimethylphenyl)ureido)phenyl sulfamate

Base Information

Chemical Name:4-(3'-(3'',5''-dimethylphenyl)ureido)phenyl sulfamate
CAS No.:1330061-67-0
Molecular Formula:C₁₅H₁₇N₃O₄S
Molecular Weight:335.384
Hs Code.:

Synonyms:4-(3'-(3'',5''-dimethylphenyl)ureido)phenyl sulfamate

Suppliers and Price of 4-(3'-(3'',5''-dimethylphenyl)ureido)phenyl sulfamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
S4
50mg
$ 470.00

Axon Medchem
CAIXInhibitorS4 99%
50 mg
$ 374.00

American Custom Chemicals Corporation
S-4 95.00%
5MG
$ 455.08

AK Scientific
4-[(3,5-Dimethylphenyl)Ureido]PhenylSulfamate
5mg
$ 187.00

Total 7 raw suppliers

Chemical Property of 4-(3'-(3'',5''-dimethylphenyl)ureido)phenyl sulfamate

Chemical Property:

Density:1.429±0.06 g/cm3(Predicted)

Purity/Quality:

98% ,99% , ^*data from raw suppliers

S4 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses S4 is a sulfamate carbonic anhydrase IX (CAIX) inhibitor in colorectal carcinoma cell lines.

Technology Process of 4-(3'-(3'',5''-dimethylphenyl)ureido)phenyl sulfamate

There total 3 articles about 4-(3'-(3'',5''-dimethylphenyl)ureido)phenyl sulfamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1380411-53-9
1-(3,5-dimethylphenyl)-3-(4-hydroxyphenyl)urea

: 1330061-67-0
4-(3'-(3'',5''-dimethylphenyl)ureido)phenyl sulfamate

Guidance literature:: With sulphamoyl chloride; In N,N-dimethyl acetamide; Inert atmosphere;
DOI:10.1021/jm300529u

Reference yield:

: 123-30-8
4-amino-phenol

: 54132-75-1
3,5-dimethylphenyl isocyanate

: 1330061-67-0
4-(3'-(3'',5''-dimethylphenyl)ureido)phenyl sulfamate

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile / 20 °C / Inert atmosphere

2: sulphamoyl chloride / N,N-dimethyl acetamide / Inert atmosphere

With sulphamoyl chloride; In N,N-dimethyl acetamide; acetonitrile;
DOI:10.1016/j.bmcl.2012.05.083