diisopropyl (2-(4-chlorophenyl)-1,3,4-thiadiazole-5-sulfonamido)(2-fluorophenyl)methylphosphonate

Base Information

Chemical Name:diisopropyl (2-(4-chlorophenyl)-1,3,4-thiadiazole-5-sulfonamido)(2-fluorophenyl)methylphosphonate
CAS No.:1257421-81-0
Molecular Formula:C₂₁H₂₄ClFN₃O₅PS₂
Molecular Weight:547.996
Hs Code.:

Synonyms:diisopropyl (2-(4-chlorophenyl)-1,3,4-thiadiazole-5-sulfonamido)(2-fluorophenyl)methylphosphonate

Suppliers and Price of diisopropyl (2-(4-chlorophenyl)-1,3,4-thiadiazole-5-sulfonamido)(2-fluorophenyl)methylphosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of diisopropyl (2-(4-chlorophenyl)-1,3,4-thiadiazole-5-sulfonamido)(2-fluorophenyl)methylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of diisopropyl (2-(4-chlorophenyl)-1,3,4-thiadiazole-5-sulfonamido)(2-fluorophenyl)methylphosphonate

There total 6 articles about diisopropyl (2-(4-chlorophenyl)-1,3,4-thiadiazole-5-sulfonamido)(2-fluorophenyl)methylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

: 1257421-86-5
C₁₃H₂₁FNO₃P

: 328527-98-6
5-(4-chlorophenyl)-1,3,4-thiadiazole-2-sulfonyl chloride

: 1257421-81-0
diisopropyl (2-(4-chlorophenyl)-1,3,4-thiadiazole-5-sulfonamido)(2-fluorophenyl)methylphosphonate

Guidance literature:: With triethylamine; In acetonitrile; at 20 ℃; for 6h;
DOI:10.3390/molecules15129046

Reference yield:

: 1126-46-1
Methyl 4-chlorobenzoate

: 1257421-81-0
diisopropyl (2-(4-chlorophenyl)-1,3,4-thiadiazole-5-sulfonamido)(2-fluorophenyl)methylphosphonate

Guidance literature:: Multi-step reaction with 5 steps

1: hydrazine hydrate / ethanol / 8 h / Reflux

2: potassium hydroxide / ethanol / 20 °C

3: sulfuric acid / -2 - 0 °C

4: hydrogenchloride; water; chlorine / 1,2-dichloro-ethane / -2 °C

5: triethylamine / acetonitrile / 6 h / 20 °C

With hydrogenchloride; sulfuric acid; water; chlorine; hydrazine hydrate; triethylamine; potassium hydroxide; In ethanol; 1,2-dichloro-ethane; acetonitrile;
DOI:10.3390/molecules15129046

Reference yield:

: 38539-88-7
potassium p-chlorobenzoylhydrazinodithioformate

: 1257421-81-0
diisopropyl (2-(4-chlorophenyl)-1,3,4-thiadiazole-5-sulfonamido)(2-fluorophenyl)methylphosphonate

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid / -2 - 0 °C

2: hydrogenchloride; water; chlorine / 1,2-dichloro-ethane / -2 °C

3: triethylamine / acetonitrile / 6 h / 20 °C

With hydrogenchloride; sulfuric acid; water; chlorine; triethylamine; In 1,2-dichloro-ethane; acetonitrile;
DOI:10.3390/molecules15129046