2-(cyclohexylmethyl)-3-cyclopropyl-4-methyl-4-phenylpent-1-en-3-ol

Base Information

• Chemical Name: 2-(cyclohexylmethyl)-3-cyclopropyl-4-methyl-4-phenylpent-1-en-3-ol
• CAS No.: 1425509-00-7
• Molecular Formula: C₂₂H₃₂O
• Molecular Weight: 312.495
• Mol file: 1425509-00-7.mol

Synonyms:2-(cyclohexylmethyl)-3-cyclopropyl-4-methyl-4-phenylpent-1-en-3-ol

Chemical Property of 2-(cyclohexylmethyl)-3-cyclopropyl-4-methyl-4-phenylpent-1-en-3-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(cyclohexylmethyl)-3-cyclopropyl-4-methyl-4-phenylpent-1-en-3-ol

There total 1 articles about 2-(cyclohexylmethyl)-3-cyclopropyl-4-methyl-4-phenylpent-1-en-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

1-cyclopropyl-2-methyl-2-phenylpropan-1-one (1340424-60-3) + 2-bromo-3-cyclohexylprop-1-ene (53608-85-8) → 2-(cyclohexylmethyl)-3-cyclopropyl-4-methyl-4-phenylpent-1-en-3-ol (1425509-00-7)

Guidance literature:

2-bromo-3-cyclohexylprop-1-ene; With tert.-butyl lithium; In diethyl ether; at -78 - -20 ℃; for 1.66667h; Inert atmosphere;

1-cyclopropyl-2-methyl-2-phenylpropan-1-one; In diethyl ether; at -78 - -10 ℃; for 1.5h; Inert atmosphere;

With ammonium chloride; In diethyl ether;

DOI:10.1021/ja400831w

Reference yield: 72.0%

2-(cyclohexylmethyl)-3-cyclopropyl-4-methyl-4-phenylpent-1-en-3-ol (1425509-00-7) + dithiocarbonic acid S-[2-(2,4-difluoro-phenyl)-2-oxo-ethyl] ester O-ethyl ester → 2-(cyclohexylmethyl)-1-cyclopropyl-5-(2,4-difluorophenyl)pentane-1,5-dione (1425508-68-4)

Guidance literature:

With dilauryl peroxide; In ethyl acetate; for 7h; Inert atmosphere; Reflux;

DOI:10.1021/ja400831w

Reference yield:

2-(cyclohexylmethyl)-3-cyclopropyl-4-methyl-4-phenylpent-1-en-3-ol (1425509-00-7) → dicumene (1889-67-4)

Guidance literature:

With dilauryl peroxide; dithiocarbonic acid S-[2-(2,4-difluoro-phenyl)-2-oxo-ethyl] ester O-ethyl ester; In ethyl acetate; Inert atmosphere; Reflux;

DOI:10.1021/ja400831w

upstream raw materials:

1-cyclopropyl-2-methyl-2-phenylpropan-1-one

2-bromo-3-cyclohexylprop-1-ene

Downstream raw materials:

2-(cyclohexylmethyl)-1-cyclopropyl-5-(2,4-difluorophenyl)pentane-1,5-dione

3-(cyclohexylmethyl)-2-cyclopropyl-6-(2,4-difluorophenyl)pyridine

dicumene