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Usage

Uses

Used in Pharmaceutical Industry:
3-Cyclohexyl-2-bromopropene is used as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Cyclohexyl-2-bromopropene serves as a crucial intermediate for the production of pesticides and other agrochemicals. Its role in these applications helps to improve crop protection and contribute to more efficient agricultural practices.
Used in Fine Chemicals Production:
3-Cyclohexyl-2-bromopropene is also utilized in the synthesis of fine chemicals, which are high-purity chemicals used in various industries such as fragrances, dyes, and coatings. Its versatility in organic synthesis makes it an essential component in creating specialized chemical products.
Used in Organic Synthesis:
As a building block in organic synthesis, 3-Cyclohexyl-2-bromopropene is used to construct a wide range of organic compounds. Its reactivity and structural features make it a valuable precursor in the chemical industry for creating new and innovative products.

Upstream product

• 22233-91-6 phenylselenocyclohexane 
• 139930-06-6 (2-bromoallyl)(phenyl)sulfane 
• 108-98-5 thiophenol 
• 626-62-0 Cyclohexyl iodide 
• 108-85-0 1-bromocyclohexane 
• 513-31-5 2-bromoallyl bromide 
• 931-50-0 cyclohexylmagnesium bromide 

Downstream Products

• 127998-29-2 1-[2-(cyclohexylmethyl)prop-2-enyl]cyclohexan-1-ol 
• 127998-28-1 2-(cyclohexylmethyl)-1-nonen-4-ol 
• 94922-19-7 1-allyl-2-(2-bromoallyl)cyclohexanol 
• 102617-51-6 methyl 2-(cyclohexylmethyl)acrylate 
• 131330-80-8 3-Cyclohexyl-2-methylenepropanoic acid 
• 1425508-85-5 3-(cyclohexylmethyl)-2-cyclopropyl-6-(2,4-difluorophenyl)pyridine 
• 1425508-80-0 8-(cyclohexylmethyl)-1-cyclopropyl-2-methyldecane-1,5,9-trione 
• 1425508-68-4 2-(cyclohexylmethyl)-1-cyclopropyl-5-(2,4-difluorophenyl)pentane-1,5-dione 
• 1425509-00-7 2-(cyclohexylmethyl)-3-cyclopropyl-4-methyl-4-phenylpent-1-en-3-ol 
• 1425508-96-8 2-(cyclohexylmethyl)-3,4-dimethyl-4-phenylpent-1-en-3-ol 
• 1379452-74-0 (R)-3-(cyclohexylmethyl)-2-cyclopentylbut-3-enenitrile 
• 1089214-31-2 2,4-bis(cyclohexylmethyl)penta-1,4-dien-3-ol 
• 118453-34-2 (3aS,11aR)-5a-Hydroxy-2-phenyl-3a,4,5,5a,6,7,8,9,9a,10,11,11a-dodecahydro-naphtho[2,3-f]isoindole-1,3-dione 
• 97196-80-0 1,1-diethoxy-4-cyclohexylbut-2-yne 

Relevant academic research and scientific papers

One-pot desymmetrizing hydroformylation/carbonyl ene cyclization process: Straightforward access to highly functionalized cyclohexanols

(Chemical Equation Presented) Rapid access to highly functionalized alkylidene cyclohexanols through a one-pot desymmetrizing hydroformylation/ carbonyl ene cyclization starting from simple bisalkenylcarbinols is reported. Mechanistic insight into the carbonyl ene reaction is given, highlighting the importance of hyperconjugative substituent effects.

Neighbouring-group influence on the ring opening of some 2-alkyl-1,1,2-tribromocyclopropanes under phase-transfer conditions

Several 2-alkyl-1,1,2-tribromocyclopropanes were treated with sodium hydroxide and ethanol under phase-transfer conditions. Ring opening gave mixtures of the corresponding acetylenic diethyl ketals and acetals. When the steric bulk of the alkyl substituent was increased acetal formation dominated, and in the case of 1,1,2-tribromo-2-(tert-butyl)cyclopropane, the acetal was formed as the only product. Springer-Verlag 2005.

Selective Mono- and Polymethylene Homologations of Copper Reagents Using (Iodomethyl)zinc Iodide

A wide range of unsaturated aryl-, alkenyl-, alkynylcopper compounds can be selectively homologated by a methylene unit using (iodomethyl)zinc iodide or bis(iodomethyl)zinc.These reactions allow the generation of mixed allylic zinc-copper compounds which can be efficiently trapped with carbonyl compounds.An application to a general preparation of functionalized α-methylene-γ-butyrolactones is described.The homologation of alkynylcoppers with (iodomethyl)zinc iodide allows a one-pot preparation of propargylic copper reagents which in the presence of a carbonyl compound provide various homopropargylic alcohols in excellent yields.In the absence of an electrophile, a clean quadruple methylene homologation of alkynylcoppers occurs to furnish dienic copper reagents.The homologation of other types of copper reagents is also possible, and carbanions at the α-position to amines as well as homoenolates of aldehydes or ketones can also be prepared by this method.

New reagents for radical allylations

Three reagents are introduced for radical allylations: 3-phenylthio-2-bromopropene, 2,3-bis(trimethylstannyl)propene, and 3-tris(trimethylsilyl)silylthiopropene.