(4S,5S,6S)-6-ethyl-5-methyl-4-(2-(1-phenyl-1H-tetrazol-5-ylsulfonyl)ethyl)-4-(trimethylsilyloxy)-tetrahydropyran-2-one

Base Information

Chemical Name:(4S,5S,6S)-6-ethyl-5-methyl-4-(2-(1-phenyl-1H-tetrazol-5-ylsulfonyl)ethyl)-4-(trimethylsilyloxy)-tetrahydropyran-2-one
CAS No.:1299358-29-4
Molecular Formula:C₂₀H₃₀N₄O₅SSi
Molecular Weight:466.634
Hs Code.:

Synonyms:(4S,5S,6S)-6-ethyl-5-methyl-4-(2-(1-phenyl-1H-tetrazol-5-ylsulfonyl)ethyl)-4-(trimethylsilyloxy)-tetrahydropyran-2-one

Suppliers and Price of (4S,5S,6S)-6-ethyl-5-methyl-4-(2-(1-phenyl-1H-tetrazol-5-ylsulfonyl)ethyl)-4-(trimethylsilyloxy)-tetrahydropyran-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4S,5S,6S)-6-ethyl-5-methyl-4-(2-(1-phenyl-1H-tetrazol-5-ylsulfonyl)ethyl)-4-(trimethylsilyloxy)-tetrahydropyran-2-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4S,5S,6S)-6-ethyl-5-methyl-4-(2-(1-phenyl-1H-tetrazol-5-ylsulfonyl)ethyl)-4-(trimethylsilyloxy)-tetrahydropyran-2-one

There total 13 articles about (4S,5S,6S)-6-ethyl-5-methyl-4-(2-(1-phenyl-1H-tetrazol-5-ylsulfonyl)ethyl)-4-(trimethylsilyloxy)-tetrahydropyran-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1299358-26-1
(4S,5S,6S)-6-ethyl-5-methyl-4-(2-(1-phenyl-1H-tetrazol-5-ylthio)ethyl)-4-(trimethylsilyloxy)-tetrahydropyran-2-one

: 1299358-29-4
(4S,5S,6S)-6-ethyl-5-methyl-4-(2-(1-phenyl-1H-tetrazol-5-ylsulfonyl)ethyl)-4-(trimethylsilyloxy)-tetrahydropyran-2-one

Guidance literature:: With hexaammonium heptamolybdate tetrahydrate; dihydrogen peroxide; In ethanol; water; at 0 - 20 ℃;
DOI:10.1055/s-0030-1259286

Reference yield:

: 1299358-14-7
(4S,5S)-5-{[tert-butyl(dimethyl)silyl]oxy}-4-methylhept-1-en-3-one

: 1299358-29-4
(4S,5S,6S)-6-ethyl-5-methyl-4-(2-(1-phenyl-1H-tetrazol-5-ylsulfonyl)ethyl)-4-(trimethylsilyloxy)-tetrahydropyran-2-one

Guidance literature:: Multi-step reaction with 8 steps

1: N,N,N',N'-tetramethylguanidine / 2 h / 20 °C / Inert atmosphere

2: hydrogenchloride; water / methanol / 2 h / 20 °C

3: pyridine; dmap / dichloromethane / -78 - -10 °C / Inert atmosphere

4: samarium diiodide / tetrahydrofuran / -78 °C / Inert atmosphere

5: 1H-imidazole; dmap / dichloromethane / 4 h / 20 °C / Inert atmosphere

6: palladium 10% on activated carbon; hydrogen / tetrahydrofuran / 2 h / 20 °C

7: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran; toluene / Inert atmosphere

8: hexaammonium heptamolybdate tetrahydrate; dihydrogen peroxide / ethanol; water / 0 - 20 °C

With pyridine; 1H-imidazole; hydrogenchloride; dmap; samarium diiodide; hexaammonium heptamolybdate tetrahydrate; palladium 10% on activated carbon; water; hydrogen; dihydrogen peroxide; triphenylphosphine; diethylazodicarboxylate; N,N,N',N'-tetramethylguanidine; In tetrahydrofuran; methanol; ethanol; dichloromethane; water; toluene; 1: Michael addition / 4: intramolecular Reformatsky reaction / 7: Mitsunobu reaction;
DOI:10.1055/s-0030-1259286

Reference yield:

: 1299358-21-6
(1S,2S)-5-(benzyloxy)-1-ethyl-2-methyl-3-oxopentyl bromoacetate

: 1299358-29-4
(4S,5S,6S)-6-ethyl-5-methyl-4-(2-(1-phenyl-1H-tetrazol-5-ylsulfonyl)ethyl)-4-(trimethylsilyloxy)-tetrahydropyran-2-one

Guidance literature:: Multi-step reaction with 5 steps

1: samarium diiodide / tetrahydrofuran / -78 °C / Inert atmosphere

2: 1H-imidazole; dmap / dichloromethane / 4 h / 20 °C / Inert atmosphere

3: palladium 10% on activated carbon; hydrogen / tetrahydrofuran / 2 h / 20 °C

4: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran; toluene / Inert atmosphere

5: hexaammonium heptamolybdate tetrahydrate; dihydrogen peroxide / ethanol; water / 0 - 20 °C

With 1H-imidazole; dmap; samarium diiodide; hexaammonium heptamolybdate tetrahydrate; palladium 10% on activated carbon; hydrogen; dihydrogen peroxide; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; dichloromethane; water; toluene; 1: intramolecular Reformatsky reaction / 4: Mitsunobu reaction;
DOI:10.1055/s-0030-1259286