3-[N-benzyloxycarbonyl-(4,4-diethoxybutyl)amino]-4-(N-benzyloxycarbonyl-1,2,5,6-tetrahydropyridin-2-yl)butyraldehyde

Base Information

Chemical Name:3-[N-benzyloxycarbonyl-(4,4-diethoxybutyl)amino]-4-(N-benzyloxycarbonyl-1,2,5,6-tetrahydropyridin-2-yl)butyraldehyde
CAS No.:309248-67-7
Molecular Formula:C₃₃H₄₄N₂O₇
Molecular Weight:580.722
Hs Code.:

Synonyms:3-[N-benzyloxycarbonyl-(4,4-diethoxybutyl)amino]-4-(N-benzyloxycarbonyl-1,2,5,6-tetrahydropyridin-2-yl)butyraldehyde

Suppliers and Price of 3-[N-benzyloxycarbonyl-(4,4-diethoxybutyl)amino]-4-(N-benzyloxycarbonyl-1,2,5,6-tetrahydropyridin-2-yl)butyraldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-[N-benzyloxycarbonyl-(4,4-diethoxybutyl)amino]-4-(N-benzyloxycarbonyl-1,2,5,6-tetrahydropyridin-2-yl)butyraldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-[N-benzyloxycarbonyl-(4,4-diethoxybutyl)amino]-4-(N-benzyloxycarbonyl-1,2,5,6-tetrahydropyridin-2-yl)butyraldehyde

There total 5 articles about 3-[N-benzyloxycarbonyl-(4,4-diethoxybutyl)amino]-4-(N-benzyloxycarbonyl-1,2,5,6-tetrahydropyridin-2-yl)butyraldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 309248-65-5
N-benzyloxycarbonyl-2-[2-N-benzyloxycarbonyl-(4,4-diethoxybutyl)amino]-but-3-enyl-1,2,5,6-tetrahydropyridine

: 309248-67-7
3-[N-benzyloxycarbonyl-(4,4-diethoxybutyl)amino]-4-(N-benzyloxycarbonyl-1,2,5,6-tetrahydropyridin-2-yl)butyraldehyde

Guidance literature:: With oxygen; copper(l) chloride; palladium dichloride; In water; N,N-dimethyl-formamide; for 6h;
DOI:10.1021/ja001688i

Reference yield:

: (4,4-Diethoxy-butyl)-{(R)-1-[(S)-1-(1,2,5,6-tetrahydro-pyridin-2-yl)methyl]-allyl}-amine

: 309248-67-7
3-[N-benzyloxycarbonyl-(4,4-diethoxybutyl)amino]-4-(N-benzyloxycarbonyl-1,2,5,6-tetrahydropyridin-2-yl)butyraldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 813 mg / dimethylformamide / 0.17 h / 20 °C

2: 76 percent / oxygen; PdCl₂; CuCl / dimethylformamide; H₂O / 6 h

With oxygen; copper(l) chloride; palladium dichloride; In water; N,N-dimethyl-formamide;
DOI:10.1021/ja001688i

Reference yield:

: 309248-35-9
methyl (1R,4S)-4-(but-3-enyl-N-nosylamino)cyclopent-2-enyl carbonate

: 309248-67-7
3-[N-benzyloxycarbonyl-(4,4-diethoxybutyl)amino]-4-(N-benzyloxycarbonyl-1,2,5,6-tetrahydropyridin-2-yl)butyraldehyde

Guidance literature:: Multi-step reaction with 5 steps

1: 2.49 g / tetrahydrofuran / 3 h / 20 °C

2: 79 percent / Cl₂[P(cyclohexyl)3]2Ru=CHPh; C₂H₄ / CH₂Cl₂ / 48 h / 35 °C

3: K₂CO₃; thiophenol / dimethylformamide / 30 h / 70 °C

4: 813 mg / dimethylformamide / 0.17 h / 20 °C

5: 76 percent / oxygen; PdCl₂; CuCl / dimethylformamide; H₂O / 6 h

With Grubbs catalyst first generation; ethene; oxygen; potassium carbonate; thiophenol; copper(l) chloride; palladium dichloride; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/ja001688i