2',4,4'-tribenzyloxy-2-(methoxymethoxy)stilbene

Base Information

• Chemical Name: 2',4,4'-tribenzyloxy-2-(methoxymethoxy)stilbene
• CAS No.: 1009814-10-1
• Molecular Formula: C₃₇H₃₄O₅
• Molecular Weight: 558.674
• Mol file: 1009814-10-1.mol

Synonyms:2',4,4'-tribenzyloxy-2-(methoxymethoxy)stilbene

Chemical Property of 2',4,4'-tribenzyloxy-2-(methoxymethoxy)stilbene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2',4,4'-tribenzyloxy-2-(methoxymethoxy)stilbene

There total 1 articles about 2',4,4'-tribenzyloxy-2-(methoxymethoxy)stilbene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C39H34O2P(1+)*Cl(1-) (1009814-08-7) + 4-benzyloxy-2-(methoxymethoxy)benzaldehyde (474295-91-5) → 2',4,4'-tribenzyloxy-2-(methoxymethoxy)stilbene (1009814-10-1)

Guidance literature:

With lithium hexamethyldisilazane; In tetrahydrofuran; at 0 - 20 ℃; for 1h;

DOI:10.1016/j.bmcl.2008.08.053

Reference yield: 86.0%

2',4,4'-tribenzyloxy-2-(methoxymethoxy)stilbene (1009814-10-1) → 2',4,4'-tribenzyloxy-2-(methoxymethoxy)bibenzyl (1009816-04-9)

Guidance literature:

With palladium on activated charcoal; hydrogen; ethylenediamine; at 20 ℃; for 12h;

DOI:10.1016/j.bmcl.2008.08.053

Reference yield:

2',4,4'-tribenzyloxy-2-(methoxymethoxy)stilbene (1009814-10-1) → C25H28O11

Guidance literature:

Multi-step reaction with 4 steps

1: 5% Pd(II)/C(eggshell); hydrogen / tetrahydrofuran / 12 h / 20 °C / 760.05 Torr

2: toluene-4-sulfonic acid / tetrahydrofuran; methanol / 2 h / Reflux

3: trimethylsilyl trifluoromethanesulfonate / dichloromethane / 0.08 h / 0 °C

4: 20% palladium(II) hydroxide on carbon; hydrogen / ethyl acetate / 12 h / 20 °C

With trimethylsilyl trifluoromethanesulfonate; 20% palladium(II) hydroxide on carbon; 5% Pd(II)/C(eggshell); hydrogen; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; dichloromethane; ethyl acetate;

DOI:10.1016/j.ejmech.2011.01.065

upstream raw materials:

C₃₉H₃₄O₂P⁽¹⁺⁾*Cl^(1-)

4-benzyloxy-2-(methoxymethoxy)benzaldehyde

Downstream raw materials:

2',4,4'-tribenzyloxy-2-(methoxymethoxy)bibenzyl

2',4,4'-tribenzyloxy-2-hydroxybibenzyl

2-(2'',3'',4''-tri-O-acetyl-β-D-xylopyranosyloxy)-2',4,4'-tribenzyloxybibenzyl

2',4,4'-trihydroxy-2-(β-D-xylopyranosyloxy)bibenzyl

Refernces